Automation without Centrifugation

Controlled Flow. Defined Washing. No Centrifuge.

Curiox replaces centrifugation with software-defined, pipette-based washing, bringing controlled flow and repeatable wash conditions directly into automated workflows.

  • Washing is defined by software-controlled flow rates
  • Samples experience gentle, low-shear liquid exchange
  • Wash conditions are repeatable and consistent across runs
  • Automation remains fully on-deck and uninterrupted

C-FREE™ Technology

Replace centrifugation with pipette-based flow

Cartoon image displaying scientists giving talk at CYTO 2026 on flow cytometry standardization

Flow cytometry standardization at CYTO 2026 — NIST, Amgen, AstraZeneca, and IMU

Dr. Lili Wang (NIST), Dr. Tom Hayday (IMU), Dr. John Ferbas (Amgen), and Dr. Raffaello Cimbro (AstraZeneca) are presenting on standardizing automated sample preparation across multi-site flow cytometry labs at CYTO 2026. Sign up and we’ll send you a copy of the recording.

C-FREE™ Pluto Products

The Pluto product family translates C‑FREE technology into deployable tools for labs at different stages of automation adoption—whether that means a compact wash station, full workstation for cell preparation, or software for your existing platforms.

Pluto ALPHA - Automated Cell Washing

Pluto ALPHA

Compact liquid handler for cell washing in a biosafety cabinet

Pluto Workstation - Automated Antibody Cocktailing and Cell Staining

Pluto Workstation

Automated liquid handler for antibody cocktailing, cell staining, and washing

Pluto Code

Pluto Code

Software library bringing C-FREE directly to your liquid handler

Pluto Code Data on Centrifuge-Free Workflows

Centrifuge-free washing using Pluto Code. Executed directly on standard liquid handling platforms without off-board centrifugation.

SLAS 2026 Scientific Poster

  • Centrifuge-free washing via a script library within native liquid handler methods
  • Comparable or improved cell retention across staining workflows
  • Portability  across Opentrons and Hamilton platforms

SLAS Exhibitor Tutorial

How Scientists from SLAS 2026 Run Centrifuge-Free Workflows with Pluto Code

Scientists from ETH Zurich and AstraZeneca shared validation data demonstrating how Pluto CODE standardizes washing, reduces variability, and accelerates assay transfer across sites.

“The staining process is fully integrated and performed on a single platform, without requiring additional hardware.”

– Speaker at SLAS 2026

Testimonials

"Standardizing high-parameter flow cytometry workflows has been a persistent challenge in research immune monitoring. The Workflow Wizard addresses this directly: our team can load an existing staining and washing protocol as a table, and the Pluto Workstation executes every step without manual intervention. That combination of immediate usability and run-to-run reproducibility is what makes it a serious tool for high-throughput immune monitoring environments."

Dr. Holden Maecker

Human Immune Monitoring Center, Stanford University; Scientific Advisor, Curiox Biosystems

We had automation for antibody cocktailing and data transfer, but washing was always the missing link. We were still carrying plates between disparate instruments, centrifuging, flicking, and resetting the workflow. Pluto finally closed that gap and integrated the full process.

Ryan Duggan

AbbVie

We replaced the standard centrifugation step with Curiox technology. Pluto can allow you to basically simulate centrifuge-free cell washing using a standard liquid handler. It’s really a nice technology. 

Raffaello Cimbro, PhD

AstraZeneca

Featured Application

Automated Antibody Cocktailing with Pluto Workstation

The Pluto Workstation automates antibody master mix preparation so panels are generated with robotic precision. Cocktailing, staining, and downstream centrifuge-free washing can all be performed on a single workstation, simplifying setup and reducing fragmented manual steps. 

Key Benefits:

Pluto Workstation Automated Flow Cell Preparation

Explore Sample Types

Meet Curiox At Our Upcoming Events

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SLAS Europe

Vienna, Austria
May 19-21, 2026

LRIG Philly

King of Prussia, PA
May 19, 2026

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CYTO

West Palm Beach, FL
June 6-10, 2026

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FOCIS

San Francisco, CA
June 9-12, 2026

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