One lesson that we’re still learning in our lab is that cells actually can be retained without a centrifuge. Because I was told by multiple people that if you don’t resuspend those cells as part of your wash, it’s not going to work and somehow the cells with the right settings in the Pluto are actually staying retained at the bottom and yet getting washed.

Curiox specializes in automated sample preparation solutions that aid in accurate and reproducible cell analysis. Our collaboration aims to leverage their next-generation sample preparation platform and look deep into cellular analysis for hematological malignancies.

We replaced the standard centrifugation step with Curiox technology. Pluto can allow you to basically simulate centrifuge-free cell washing using a standard liquid handler. It’s really a nice technology.