CELL AND GENE THERAPY

Get fast, consistent and gentle cell processing for highly reproducible workflows

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Gentle washing for critical workflows in cell-based therapeutics.

Lower the CVs and save FTE time from research to manufacturing.

Real world data from cell therapy companies.

Links to related content for cell and gene therapy.

Overview

CHANGE THE WAY YOU PROCESS CELLS TO
GET RELIABLY CONSISTENT DATA.

Cell therapy processing

New and improved with a touchscreen for easy menu selection, as well as a buffer exchanger for automated startup and shutdown sequences, the HT2000 washer is available as a stand-alone platform or as part of a fully-automated solution - the AUTO1000™.

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“The Laminar Wash’s performance allows us to get very tight control over populations with very tight CV’s largely due to the fact of the clear separations between populations. The maintained ability to detect rare populations is important as we detect the next round of cell therapy products.”

Arnaud Colantonio, PhD. Associate Director of Analytical Development at AdiCet Bio, now with Kite Pharma
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Technology

TRADITIONAL CENTRIFUGATION

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LAMINAR WASH TECHNOLOGY

Comparison of an immuno-staining workflow for the preparation of a single cell suspension for flow cytometry analysis. Laminar Wash technology is equally effective in washing but without the use of a centrifuge.

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Benefits

BENEFITS OF LAMINAR WASH FOR SINGLE-CELL SEQUENCING

The use of Laminar Wash can improve data from research to analytical development to manufacturing quality control. The Laminar Wash technology can provide the following to cell and gene therapy applications:

  • Lower CVs
  • Improved reproducibility among operators, times, and locations
  • Reduce hands-on time
  • Save FTE time
Featured Resource

CENTRIFUGE-LESS RED BLOOD CELL LYSIS AND IMMUNOSTAINING WHOLE BLOOD FOR FLOW CYTOMETRY USING LAMINAR WASH™ TECHNOLOGY

Scientific Data

DATA USING THE LAMINAR WASH SYSTEMS

Improved Resolution of Rare Cell Populations

Laminar Wash™ consistently gives better resolution between populations and less spread within populations, making gating strategy easier for operators and algorithms. Data shown here of rare gamma-delta T cell types, courtesy of Adicet Bio, a Curiox customer.

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Improved Condition of Rare Cells

Laminar Wash™ enables better preservation of rare cell types. Data shown here of MAIT, Treg, and gamma-delta T cells in a whole blood depletion assay.

Recent Publications View All Publications >

    Peritoneal Fluid Cytokines Reveal New Insights of Endometriosis Subphenotypes

    Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

    2020 | Nature Cancer

    Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms

    2019 | JoVE

    TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens

    2019 | JoVE

Recent Publications View All Publications >

    Peritoneal Fluid Cytokines Reveal New Insights of Endometriosis Subphenotypes

    2020  |  Nature Cancer

    Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

    2020  |  Nature Cancer

    Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms

    2020  |  Nature Cancer

    TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens

    2020  |  Nature Cancer

Get Started

AUTOMATE YOUR FLOW CYTOMETRY WORKFLOW

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FEATURED PRODUCTS

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Laminar Wash HT2000

A reliable and easy-to-use benchtop instrument for high-throughput flow cytometry labs.

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Laminar Wash AUTO 1000

Complete Automation Solution for Surface Staining and Intracellular Staining for Flow Cytometry.

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Laminar Wash Mini

An affordable, benchtop instrument for low-throughput sample preparation for flow cytometry.