Fully automate your workflows with an alternative (at last!) to centrifugation.
Laminar Wash technology makes automation easy compared to integrating a centrifuge.
Automate your workflow and save FTE time.
Data from applications that benefit from automation.
Links to useful content regarding automation.
CHANGE THE WAY YOU PROCESS CELLS TO GET RELIABLY CONSISTENT DATA.
AUTOMATED SAMPLE PREP
“I think the Laminar Wash technology is a prime device for creating an automated flow cytometry station ”
Dr. Arnuad Colantonio, AdiCet Bio, now with Kite Pharma
LAMINAR WASH TECHNOLOGY INTEGRATION WITH ROBOTICS
Centrifuges have been the only solution to automate suspension cell assays due to the need to wash cells during many assays. However, centrifuges have a number of limitations and require many steps to integrate. Centrifugation of suspension cells is a roadblock to otherwise easy automation.
Laminar Wash technology systems can be easily integrated into automation systems for methods such as flow cytometry, single cell sequencing, mass cytometry and in application areas such as CMC/Process Development, COVID-19/infectious diseases, tumor microenvironment, vaccine development.
BENEFITS OF LAMINAR WASH FOR AUTOMATED WORKFLOWS
Laminar Wash technology makes it easy for applications that require a high degree of automation such as screening final product for cell therapeutics. Laminar Wash system integration can replace centrifuge integrations and only require one robotic movement instead of over 20 movements. Integration using Laminar Wash technology can:
- Reduce hands-on time and save FTE resources
- Lower the CVs of results
- Easily allow integration on-deck or off-deck
S-LAB PRO WITH A CURIOX LAMINAR WASH HT2000 INTEGRATION
DATA USING THE LAMINAR WASH SYSTEMS
Reproducibility of Low Numbers of Cells
Laminar Wash™ shows consistently higher cell retention compared to traditional centrifugation, even at low cell numbers. Data shown using isolated naive T-cells from freshly-thawed PBMCs, at starting cell numbers of 10k, 50k, and 100k. Actual cell counts of CD3+ and %CD3+ in singlets demonstrate consistent higher cell retention rates compared to equal numbers of washes.
Increased Reproducibility of Data from Critical Samples
Laminar Wash™ technology demonstrates greater reproducibility between replicates compared to traditional centrifugation. Data shown here in a flow cytometric crossmatch assay (FXCM), widely used in human leukocyte antigen (HLA) labs to predict donor-recipient compatibility. Using three test sera and two controls in eight replicates, LW™ produced a lower coefficient of variance in B-cell median channel fluorescence (MCF) values of 7.9%, versus 12.4% in the centrifugation method. Higher MCF values on the positive control also gave FCXM greater sensitivity, which is of great value in clinical settings.
ALL YOU NEED TO KNOW ABOUT THE LAMINAR WASH HT2000 SYSTEM
AUTOMATE YOUR FLOW CYTOMETRY WORKFLOW