AUTOMATED WORKFLOWS

Fully automate your workflows with an alternative (at last!) to centrifugation.

Automated Workflows-resize

Laminar Wash technology makes automation easy compared to integrating a centrifuge.

Automate your workflow and save FTE time.

Data from applications that benefit from automation.

Links to useful content regarding automation.

Overview

CHANGE THE WAY YOU PROCESS CELLS TO
GET RELIABLY CONSISTENT DATA.

AUTOMATED SAMPLE PREP

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“I think the Laminar Wash technology is a prime device for creating an automated flow cytometry station ”

Dr. Arnuad Colantonio, AdiCet Bio,
now with Kite Pharma
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Technology

LAMINAR WASH TECHNOLOGY INTEGRATION WITH ROBOTICS

Centrifuges have been the only solution to automate suspension cell assays due to the need to wash cells during many assays. However, centrifuges have a number of limitations and require many steps to integrate. Centrifugation of suspension cells is a roadblock to otherwise easy automation.

Laminar Wash technology systems can be easily integrated into automation systems for methods such as flow cytometry, single cell sequencing, mass cytometry and in application areas such as CMC/Process Development, COVID-19/infectious diseases, tumor microenvironment, vaccine development.

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_HT2000 with SLAB-New
Benefits

BENEFITS OF LAMINAR WASH FOR AUTOMATED WORKFLOWS

Laminar Wash technology makes it easy for applications that require a high degree of automation such as screening final product for cell therapeutics. Laminar Wash system integration can replace centrifuge integrations and only require one robotic movement instead of over 20 movements. Integration using Laminar Wash technology can:

  • Reduce hands-on time and save FTE resources
  • Lower the CVs of results
  • Easily allow integration on-deck or off-deck
Featured Resource

S-LAB PRO WITH A CURIOX LAMINAR WASH HT2000 INTEGRATION

Scientific Data

DATA USING THE LAMINAR WASH SYSTEMS

Reproducibility of Low Numbers of Cells

Laminar Wash™ shows consistently higher cell retention compared to traditional centrifugation, even at low cell numbers. Data shown using isolated naive T-cells from freshly-thawed PBMCs, at starting cell numbers of 10k, 50k, and 100k. Actual cell counts of CD3+ and %CD3+ in singlets demonstrate consistent higher cell retention rates compared to equal numbers of washes.

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Increased Reproducibility of Data from Critical Samples

Laminar Wash™  technology demonstrates greater reproducibility between replicates compared to traditional centrifugation. Data shown here in a flow cytometric crossmatch assay (FXCM), widely used in human leukocyte antigen (HLA) labs to predict donor-recipient compatibility. Using three test sera and two controls in eight replicates, LW™ produced a lower coefficient of variance in B-cell median channel fluorescence (MCF) values of 7.9%, versus 12.4% in the centrifugation method. Higher MCF values on the positive control also gave FCXM greater sensitivity, which is of great value in clinical settings.

Recent Publications View All Publications >

    Peritoneal Fluid Cytokines Reveal New Insights of Endometriosis Subphenotypes

    Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

    2020 | Nature Cancer

    Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms

    2019 | JoVE

    TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens

    2019 | JoVE

Recent Publications View All Publications >

    Peritoneal Fluid Cytokines Reveal New Insights of Endometriosis Subphenotypes

    2020  |  Nature Cancer

    Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

    2020  |  Nature Cancer

    Post-hoc assessment of the immunogenicity of three antibodies reveals distinct immune stimulatory mechanisms

    2020  |  Nature Cancer

    TLR4 agonist protects against Trypanosoma cruzi acute lethal infection by decreasing cardiac parasite burdens

    2020  |  Nature Cancer

Get Started

AUTOMATE YOUR FLOW CYTOMETRY WORKFLOW

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FEATURED PRODUCTS

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Laminar Wash HT2000

A reliable and easy-to-use benchtop instrument for high-throughput flow cytometry labs.

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Laminar Wash AUTO 1000

Complete Automation Solution for Surface Staining and Intracellular Staining for Flow Cytometry.

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Laminar Wash Mini

An affordable, benchtop instrument for low-throughput sample preparation for flow cytometry.