MASS CYTOMETRY

Improve your mass cytometry data by reducing background and enhancing cell retention.

Mass Cytometry-resize

Laminar Wash can help you achieve less data variation between samples by gentle washing.

Reduce debris and enhance cell retention in mass cytometry sample preparation.

See examples of reduced variation and more intact singlets compared to centrifugation.

Links to useful resources related to mass cytometry.

Overview

CHANGE THE WAY YOU PROCESS CELLS TO
GET RELIABLY CONSISTENT DATA.

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“The one thing which I didn't expect it here is that you reduce usage of antibody with roughly 50% and we've preserved signal and reproducibility.”

Jorgen Adolfsson, Linkoping University
Flow Cytometry Sample Preparation
Technology

TRADITIONAL CENTRIFUGATION

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LAMINAR WASH TECHNOLOGY

Mass cytometry protocols can be quite harsh on the cells and Laminar Wash technology treats them gently as compared to centrifugation, which can result in more singlets.

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Benefits

BENEFITS OF LAMINAR WASH FOR MASS CYTOMETRY

Mass cytometry experiments are expensive and time consuming. Make sure all of your samples produce good data with Laminar Wash technology.

  • Reduce debris, background, artifacts and clogging
  • Enhance cell retention
  • Improve resolution
  • Lower the CVs of data
Featured Resource

BENEFITS OF USING THE CURIOX LAMINAR WASH™ SYSTEM IN MASS CYTOMETRY EXPERIMENTS

Scientific Data

DATA USING THE LAMINAR WASH SYSTEMS

Generate More Intact Singlets Compared to Centrifugation

A 25 isotope-labelled panel was used on PBMC samples starting with one million cells. Samples were then prepared using either Laminar Wash technology or centrifugation.
The frequency of singlets is higher in the Laminar Wash prepared samples. The number of intact cells was also significantly greater with the Laminar Wash treated samples.

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Increased Reproducibility Compared to Centrifugation

In this t-SNE plot, the cells cluster depending upon the expression of all 25 markers. The Laminar Wash technology prepared replicates appear to be homogenous, meaning that the samples are indistinguishable from each other when clustered. The cluster of cells prepared using centrifugation shows three very unique samples within the cluster, meaning a cell at one end of the cluster is very different from one on the other end of the cluster.

Recent Publications View All Publications >

    Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction

    2021 | Nature Portfolio Preprint

    Insights into adult atopic dermatitis heterogeneity derived from circulating biomarker profiling in patients with moderate-to-severe disease

    2021 | Wiley Online Library

    Large scale cytokine profiling uncovers elevated IL12‑p70 and IL‑17A in severe pediatric acute respiratory distress syndrome

    2021 | Scientific Reports

    Primary Human Dendritic Cells and Whole-Blood Based Assays to Evaluate Immuno-Modulatory Properties of Heat-Killed Commensal Bacteria

    2021 | Vaccines

Recent Publications View All Publications >

    Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction

    2021 | Nature Portfolio Preprint

    Insights into adult atopic dermatitis heterogeneity derived from circulating biomarker profiling in patients with moderate-to-severe disease

    2021 | Wiley Online Library

    Large scale cytokine profiling uncovers elevated IL12‑p70 and IL‑17A in severe pediatric acute respiratory distress syndrome

    2021 | Scientific Reports

    Primary Human Dendritic Cells and Whole-Blood Based Assays to Evaluate Immuno-Modulatory Properties of Heat-Killed Commensal Bacteria

    2021 | Vaccines

Get Started

AUTOMATE YOUR FLOW CYTOMETRY WORKFLOW

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FEATURED PRODUCTS

2
Laminar Wash HT2000

A reliable and easy-to-use benchtop instrument for high-throughput flow cytometry labs.

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Laminar Wash AUTO 1000

Complete Automation Solution for Surface Staining and Intracellular Staining for Flow Cytometry.

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Laminar Wash Mini

An affordable, benchtop instrument for low-throughput sample preparation for flow cytometry