MULTIPLEX IMMUNOASSAYS

Save sample and reduce costs by miniaturizing your multiplex immunoassays.

Multiplex Immunoassays-new

DropArray Technology allows you to easily miniaturize your multiplex assays.

Increase the number of samples you can run from a single kit.

See published data from miniaturized multiplex cytokine assays.

Useful links for multiplex immunoassays.

Overview

MINIATURIZE YOUR MULTIPLEX IMMUNOASSAYS TO SAVE MONEY AND SAMPLE

Reliable Data from Miniaturization

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"...the DA-Bead method for analysis was comparable to, if not superior to, the conventional method in terms of consistency/precision, accuracy, sensitivity and dynamic range and these results are not specific to sample type, reagents, or commercial vendor."

Leroy Versteeg, Baylor College of Medicine
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Technology

THE CURIOX DA-BEAD PLATE

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TRADITIONAL PLATE TECHNOLOGY

A) Incubation method principle in traditional plate (left) and DA-Bead Plate (right). Beads are freely floating with shaking in traditional well at 75µl volume vs. beads are fixed in a 15 µl drop in DA-Bead Plate by a magnet below the well and shaken.

(B) Washing method principle in traditional plate (left) and DA-Bead Plate (right). Magnet array with traditional plate either super packs beads at the side of a traditional well or keep beads as a monolayer resulting in aspiration of beads and/or incomplete washing with the nozzle/pipet based dispenser. Conversely, DA-Bead Plate magnet configuration maintains beads as a monolayer (right) resulting in complete washing with gentle laminar flow and minimal residual wash buffer leftover.

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DropArray Bead Plates
Benefits

BENEFITS OF DROPARRAY FOR MULTIPLEX IMMUNOASSAYS

Multiplex bead-based assays are robust and generate highly sensitive data from a variety of samples types. However, these assays are costly and involve expensive reagents and often valuable samples. Curiox’s new DropArray™ plates allow users to analyze the same number of analytes at a fraction of the cost and sample consumption. DropArray™ plates use 5-fold smaller volumes, so the same amount of reagent can produce 5x more data points.

  • A 5-fold miniaturization reduces total assay costs by 60–80%
  • DropArray™ plates allow 5x more wells to be run from a single assay kit
Featured Resource

BEAD-BASED CYTOKINE ASSAY ON WALL LESS PLATES: DIRECT COMPARISON TO CONVENTIONAL PLATE ASSAY

Scientific Data

DATA USING THE LAMINAR WASH SYSTEMS

Peritoneal Fluid Cytokine Multiplex Analysis
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Multiplex Immunoassay for a Cytokine Re-stimulation Assay

Recent Publications View All Publications >

    Silicone Oil Particles in Prefilled Syringes With Human Monoclonal Antibody, Representative of Real-World Drug Products, Did Not Increase Immunogenicity in In Vivo and In Vitro Model Systems

    2020 | Journal of Pharmaceutical Sciences

    Transferring Luminex® cytokine assays to a wall-less plate technology: Validation and comparison study with plasma and cell culture supernatants

    2017 | Journal of Immunological Methods

    Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

    2020 | Nature Cancer

    Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

    2017 | Nature

Recent Publications View All Publications >

    Silicone Oil Particles in Prefilled Syringes With Human Monoclonal Antibody, Representative of Real-World Drug Products, Did Not Increase Immunogenicity in In Vivo and In Vitro Model Systems

    2020  |  Nature Cancer

    Transferring Luminex® cytokine assays to a wall-less plate technology: Validation and comparison study with plasma and cell culture supernatants

    2020  |  Nature Cancer

    Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation

    2020  |  Nature Cancer

    Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

    2020  |  Nature Cancer

Get Started

MINIATURIZE YOUR MULTIPLEX IMMUNOASSAYS

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FEATURED PRODUCTS

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Drop Array Instruments

Reliable Multiplex Immunoassay Data from Miniaturization

DropArray Bead Plates
Drop Array Bead Plates

Wall-less plate technology for miniaturizing bead-based immunoassays enabling small sample volumes

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Laminar Wash MINI

An affordable, benchtop instrument for low-throughput sample preparation for flow cytometry