Brochure— HT2100 System
1-page flyer for the Curiox C-FREE Pluto System
Higher debris removal–CRX-CRL_TIL-whitepaper_apr2021.pdf
https://staging.curiox.com/wp-content/uploads/2024/08/CRX-CRL_TIL-whitepaper_apr2021.pdf
Breathe Easy with Better Models
Now Watching Research for Activating Macrophages and Dendritic Cells with Nanomedicine in Lung Carcinoma https://youtu.be/wljKOIcYsUM Macrophages can mediate phagocytosis of cancer cells and cytotoxic tumor killing, and engage in effective bidirectional interactions with components of the innate and adaptive immune system. Given the continuous recruitment of myelomonocytic cells into tumor tissues, macrophages are candidates for […]
User Manual—HT2100 System
Laminar Wash HT2100 Station User Manual
Future-Proofing Single Cell Applications
Now Watchinghttps://youtu.be/wL2tsRsL9TA Technology has evolved from those early days of batching thousands of cells together to decrypt the millions of base pairs that make up genetic information. Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq), brings together surface protein phenotyping (similar to flow cytometry) and single-cell RNA sequencing (scRNA-seq). This is achieved by using […]
The Direct Reading Grid – How it Works
Now Watchinghttps://youtu.be/_wdesbdI5ZkIn this video provides walk-throughs on pairing the Direct Reading Grid (DRG) with the Laminar Wash™ (LW) Plate to create the DRG & LW Plate Unit as well as pipetting, handling, transferring, and Big Bear Vortexing with the DRG and LW Plate Unit.
Getting to the Heart of the Matter: Novel Analytical Technologies Provide a New Perspective on a Complex Organ
Now Watchinghttps://www.youtube.com/watch?v=R-YT0iVN86c The heart is a 380-million-year-old organ, yet we do not have a complete understanding of the molecular landscape in the normal human adult heart. Of the many molecule classes present in the heart, we are especially lacking in our understanding of the cell surface proteins present on different cell types in the heart. […]
High-throughput workflow leveraging spectral flow cytometry and CITE-seq to characterize human bone marrow across race and gender
Song, B., Zhang, X., Bennett, S., Ma, S., Ferchen, K., Salomonis, N., & Grimes, H. L. (2023). The Journal of Immunology, 210(1_Supplement), 250.13. https://doi.org/10.4049/jimmunol.210.supp.250.13 Characterizing human bone marrow is challenging due to heterogeneity of cell types, and the rarity of some populations. To address this, we developed a workflow that bridges CITE seq and flow […]
Undoing Roadblocks with the HT2000 and PAA
Now Watchinghttps://www.youtube.com/watch?v=eU5TyFURoRc Laminar Wash™ HT 2000 Sample Preparation System PLUS the Peak Analysis and Automation (PAA) S-Lab Automated Plate Handler integration Automation is the key to solving “road blocks” of all kinds. Automated processes minimize variability, eliminate error, and increase throughput. Whether it is the toll road systems or laboratory workflows such as sample preparation, […]
Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction
READ NATURE PORTFOLIO PREPRINT Researchers at the University of Chicago used their Laminar Wash HT2000 system to safely prepare peripheral immune cells from COVID-19 patients with moderate and severe disease for flow cytometry in a biosafety cabinet. This preprint manuscript in a Nature family journal reveals how increased IL-6 and CCL2 in patients with severe […]