High-throughput antibody discovery to cell surface proteins

Advances in the field of flow cytometry, particularly in the areas of plate-based sampling and high-throughput assays have greatly enabled antibody discovery processes. A major consideration with high-throughput flow cytometry has been the time and workflow for removing non-specific antibody binding to cells or protein coated beads by washing via centrifugation. No-wash flow-based assays alleviate these issues but often yield misleading results.

In this recent presentation at SLAS2023, Ben Hoffstrom, Ph.D. (UCLA) and Nadiezda Fernandez Oropeza, Ph.D. (Curiox Biosystems) address the limitations of these outdated methods and establish the Laminar Wash System as an innovative solution.

Watch this presentation to learn more about:

• Major considerations with high-throughput antibody discovery
• Comparison of antibody discovery workflows (No wash, Centrifugation vs Laminar Wash™)
• Automated integration of the Laminar Wash™ System