Defining the bone marrow atlas with high-dimensional biology via a novel CITE-seq workflow

Now Watchinghttps://youtu.be/hD4OV9vf-Ak Single-cell multimodal approaches and machine learning are transforming analysis of the human hematopoietic progenitor compartment. Cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) enables coupled surface protein and transcriptome profiling, revealing genomic programs underlying progenitor states. This webinar will present groundbreaking work establishing a high-resolution human bone marrow single-cell atlas using paired […]

An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors

Zhang, X., Song, B., Carlino, M. J., Li, G., Ferchen, K., Chen, M., Thompson, E. N., Kain, B. N., Schnell, D., Thakkar, K., Kouril, M., Jin, K., Hay, S. B., Sen, S., Bernardicius, D., Ma, S., Bennett, S. N., Croteau, J., Salvatori, O., . . . Grimes, H. L. (2024). Nature Immunology, 25(4), 703–715. https://doi.org/10.1038/s41590-024-01782-4 […]

Enabling Single-cell Multiomics and Cell Hashing in Studies with Limited Numbers of Cells

Now Watchinghttps://youtu.be/LagyuoWvELo Our October 19, 2021 webinar featured University of Gothenburg Associate Professor of Immunology Mats Bemark, Ph.D. and Curiox Biosystems Marketing & Content Manager, Geoffrey Feld, Ph.D. Dr. Bemark studies mucosal immunology, with particular focus on the gut and gut-related infections like cholera, and recently has been working on COVID-19 with human severe disease samples. His […]

Laminar Wash MINI000 Virtual Demonstration with CITE-Seq Protocol

Now Watchinghttps://www.youtube.com/watch?v=HrvllFVj3K0 This video demonstrates the daily operation and utility of the Laminar WashTM MINI1000 system, hosted by Curiox Biosystems scientist Amira Amilia, and features a common protocol example in setting up a CITE-Seq (Cellular Indexing of Transcriptomes and Epitopes by Sequencing) staining assay. Comprised of a proprietary 16-well “wall-less” strip and a fluidics instrument, the MINI1000 is the […]