Ex vivo T cell differentiation in adoptive immunotherapy manufacturing: Critical process parameters and analytical technologies

Sixun Chen, Tan Dai Nguyen, Kang-Zheng Lee, Dan Liu, https://doi.org/10.1016/j.biotechadv.2024.108434  Adoptive immunotherapy shows great promise as a treatment for cancer and other diseases. Recent evidence suggests that the therapeutic efficacy of these cell-based therapies can be enhanced by the enrichment of less-differentiated T cell subpopulations in the therapeutic product, giving rise to a need for […]