Immunomodulatory effects and improved outcomes with cisplatin-versus carboplatin-based chemotherapy plus atezolizumab in urothelial cancer
Galsky, M. D., Guan, X., Rishipathak, D., Rapaport, A. S., Shehata, H. M., Banchereau, R., Yuen, K., Varfolomeev, E., Hu, R., Han, C., Li, H., Liang, Y., Vucic, D., Wang, L., Zhu, J., Yu, H., Herbst, R. H., Hajaj, E., Kiner, E., . . . Mariathasan, S. (2024). Cell Reports Medicine, 5(2), 101393. https://doi.org/10.1016/j.xcrm.2024.101393 In metastatic urothelial […]
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumour
READ NATURE Zappasodi R, Serganova I, Cohen IJ, et al. CTLA-4 blockade drives loss of T reg stability in glycolysis-low tumours. Nature. 2021 Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Functional profiling of nucleotide Excision repair in breast cancer
READ JOVE Rajkumar-Calkins AS, Szalat R, Dreze M, et al. DNA Repair. 2019;82:102697. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Nucleotide excision repair is a potential therapeutic target in multiple myeloma
READ JOVE Szalat R, Samur MK, Fulciniti M, et al. Nucleotide excision repair is a potential therapeutic target in multiple myeloma. Leukemia. 2017;32:111. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation
READ NATURE CANCER Wu L, Seung E, Xu L, et al. Trispecific antibodies enhance the therapeutic efficacy of tumor-directed T cells through T cell receptor co-stimulation. Nature Cancer. 2020;1(1):86-98. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors
READ JOVE Francica BJ, Ghasemzadeh A, Desbien AL, et al. Cancer Immunology Research. 2018;6(4):422. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Tetravalent biepitopic targeting enables intrinsic antibody agonism of tumor necrosis factor receptor superfamily members
READ PUBMED Yang Y, Yeh SH, Madireddi S, et al. mAbs. 2019;11(6):996-1011. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.