Immunopeptidomic MHC-I Profiling and Immunogenicity Testing Identifies Tcj2 as a New Chagas Disease mRNA Vaccine Candidate
Versteeg, L., Adhikari, R., Robinson, G., Lee, J., Wei, J., Islam, N., Keegan, B., Russell, W. K., Poveda, C., Villar, M. J., Jones, K., Bottazzi, M. E., Hotez, P., Tijhaar, E., & Pollet, J. (2024). PLoS Pathogens, 20(12), e1012764. https://doi.org/10.1371/journal.ppat.1012764 Trypanosoma cruzi is a protozoan parasite that causes Chagas disease. Globally 6 to 7 million […]
How to wash away barriers to therapeutic cancer vaccine development

Developing neoantigen-based cancer vaccines necessitates comprehensive cellular characterization for iterative therapeutic improvement, which Laminar Wash™ systems may facilitate at multiple steps. Vaccines are probably the second-most effective advancement in the annals of human medicine, after sanitation. Most of us recognize the value of vaccines in infectious disease. Yet, swept under the rug amongst the COVID-19 global pandemic is another form of immune-boosting injection combating a terrible […]
Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection
READ JOVE Versteeg L, Wei J, Liu Z, et al. PLOS Neglected Tropical Diseases. 2020;14(2):e0008057. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction
READ JOVE Akiyama H, Miller CM, Ettinger CR, Belkina AC, Snyder-Cappione JE, Gummuluru S. Nature Communications. 2018;9(1):3450. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm
READ JOVE Briggs N, Wei J, Versteeg L, et al. PLOS Pathogens. 2018;14(8):e1007273. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.