C-FREE™ Pluto Code – Replace Centrifugation with Pipette-Based Automation
Home / Replace Centrifugation with Pipette-Based Automation Many cell workflows still rely on repeated spin–decant–resuspend steps. C-FREE™ Pluto Code introduces an alternative: pipette-based automation that enables wash-and-mix sequences, without relying on centrifugation. Install the Pluto Code script library into your existing liquid handler for full walkaway workflows, no hardware upgrades required. Request Info C-FREE™ Pluto […]
Evaluating centrifuge-free automation after SLAS
Thank you for visiting Curiox at SLAS and engaging with our centrifuge-free automation demonstrations! This page brings together the data, examples, and context automation teams most often asked for when evaluating whether centrifugation can be replaced by your liquid handler. Use the resources below to assess function, performance, and deployment options. C-FREE™ Pluto Code: Software-defined […]
Validated 384-Well C-FREE™ Washing for High-Throughput Cell Prep

Validated 384-Well Centrifuge-Free Washing for High-Throughput Cell Prep Technical and biological validation of centrifuge-free washing at 384-well scale using the C-FREE™ Pluto platform. Enabling high-throughput cell prep automation Moving to 384-well formats increases throughput and reduces reagent use—but washing at this scale introduces real risks: sample loss, uneven retention, and assay variability. This application note […]
From Gentle Wash to Harmonized Workflows: How the Field Scaled Next

By Melvin Lye, Curiox Biosystems For much of the history of flow cytometry, centrifugation has been treated as an accepted compromise. It is efficient, familiar, and deeply embedded in laboratory practice. At the same time, its limitations (cell loss, mechanical stress, and operator-dependent variability) have long been recognized, even if rarely interrogated explicitly in published work. As […]
Harmonization in Cell Preparation: Preserving Data Comparability Across Sites, CROs, and Automation Platforms

By Mallory Griffin, Curiox Biosystems The problem: comparable data starts upstream Cell-based assays have benefited from major advances in instrumentation, reagents, and analysis software. Measurement technologies and data analysis are increasingly automated, standardized, and shared across organizations. Cell preparation, however, remains one of the least controlled parts of the workflow. Even when the same protocol […]
Getting to the Heart of the Matter: Novel Analytical Technologies Provide a New Perspective on a Complex Organ – Access
Thank You — Your Webinar Is Ready Getting to the Heart of the Matter: Novel Analytical Technologies Provide a New Perspective on a Complex Organ Featuring Rebekah L. Gundry, PhD, FAHA of the University of Nebraska Medical Center. Access the full recording below. https://youtu.be/ZdVKNuOPXXM Resources & Next Steps Learn More about C-FREE™ Technology Pluto Workstation […]
Curiox at SLAS 2026

Curiox at SLAS 2026 Bring Centrifuge-Free Automation to Your Liquid Handler with C-FREE™ Pluto CODE Exhibitor Tutorial · February 9, 2026 · 2–3 PM EST Curiox Booth #2140 Book a Meeting EXHIBITOR TUTORIAL Replace Your Centrifuge with a Pipette Robot: Centrifuge-Free Automation with C-FREE™ Pluto CODE February 9, 2026 · 2–3 PM EST See on […]
The Automation Conversation: What Pharma and Flow Cores Can Learn from Each Other
Thank You — Your Webinar Is Ready The Automation Conversation: What Pharma and Flow Cores Can Learn From Each Other Featuring Ryan Duggan (AbbVie) and David Leclerc (University of Chicago). Access the full recording below. https://youtu.be/-CNrIJ_fBwE Resources & Next Steps Learn More about C-FREE™ Technology Pluto Workstation Automating Antibody Cocktailing Ready to discuss your workflow? […]
The Automation Conversation: What Pharma and Flow Cores Can Learn from Each Other
WEBINAR The Automation Conversation: What Pharma and Flow Cores Can Learn from Each Other Experts from AbbVie and GLIIFCA on modernizing flow cytometry workflows with automation “We had a bunch of disparate instruments and I had to carry plates from one instrument to another…The missing link was washing.” -Ryan Duggan AbbVie Get the Recording 60 […]
Validating C-FREE™ Pluto Wash: Extending Laminar Wash™ Principles

WHITEPAPER From Laminar Wash™ to Pluto Wash™ — A Fluid‑Dynamics Validation Establishing Reliability of C-FREE™ Pluto Wash Technology through Proven Laminar Wash™ Principles: A Fluid Dynamics–Based Validation Automated. Centrifuge-less. Proven.This whitepaper demonstrates how the C-FREE™ Pluto Wash platform replicates the trusted Laminar Wash™ physics—delivering equivalent recovery, staining, and reproducibility in a fully automated workflow. See […]