Technology Overview

At Curiox, our vision for sample preparation technology is clear: to redefine the way labs operate by offering innovative solutions that automate and optimize workflows, enhance data quality, and reduce hands-on time. Our technologies, Laminar Wash and C-FREE, are engineered to overcome the limitations of traditional centrifugation, providing researchers with reliable, efficient, and scalable alternatives for cell and bead processing. 

Laminar Wash Technology

Curiox Laminar Wash technology employs a proprietary laminar flow mechanism to gently wash suspension cells, delivering fast, consistent, and high-quality results with minimal cell loss. This technology is particularly beneficial for applications where quantitative flow cytometry is critical, such as drug discovery, cell therapy, and biomarker identification. By eliminating centrifugation, laminar wash reduces mechanical stress on cells, preserves cell viability, and enhances data resolution. It also significantly cuts down sample handling time, reducing labor costs and minimizing human error.  Learn more.

C-FREE Technology

C-FREE technology, as utilized in the Curiox C-FREE Pluto System, redefines sample preparation by leveraging controlled fluid dynamics to perform buffer exchanges without centrifugation. Unlike laminar wash, which mainly focuses on gentle cell handling, the Pluto system automates the washing of both cells and beads using a robotic pipette system. This approach enables precise fluid control, minimizing particle loss and eliminating the need for pellet formation, a common requirement in centrifugation-based methods. Learn more.

Compare and Contrast: Laminar Wash vs. C-FREE Technology on the Pluto System

While both laminar wash and the C-FREE Pluto technologies are designed to replace most centrifugation in sample preparation, they serve different needs within laboratory workflows.

  • Laminar Wash gently handles suspension cells using a unique laminar flow technique, making it ideal for applications requiring high cell viability, such as flow cytometry and cell therapy.
  • C-FREE Pluto technology is engineered for comprehensive automation, providing a centrifuge-free solution for washing both cells and beads. Its robotic pipette system and fluid dynamics offer high precision, making it perfect for labs looking to fully automate their sample preparation processes and enhance reproducibility.

Discover The Best Fit For Your Lab

Whether you prioritize gentle cell handling or complete workflow automation, Curiox offers solutions tailored to your research needs. Explore Laminar Wash and C-FREE Pluto technologies to find the perfect fit for your laboratory’s sample preparation requirements. Contact us to determine which technology aligns best with your goals and take the first step towards revolutionizing your lab operations. 

Related Products

  • Venus System

  • Pluto System

Key Resources

Simplify your path to new technology while experiencing customizable automation firsthand

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Specification Sheet—Venus System

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Specification Sheet—Pluto LT System

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Specification Sheet—Pluto MT System

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Breaking a Stereotype: Suspension Cells and Beads May Not Require Centrifugation

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POSTER—Replacing the centrifuge to increase T-cell recovery and generate consistent data: The Laminar Wash™ approach

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Higher debris removal–CRX-CRL_TIL-whitepaper_apr2021.pdf

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POSTER—2024-A Centrifuge-Less Approach With the Pluto System

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