Laminar Wash Technology

Curiox Laminar Wash™ technology (laminar wash) uses a proprietary laminar flow technology to gently wash your suspension cells. This process yields fast, consistently reliable results with higher cell retention, increased resolution, and superior data quality. This technology is ideal when quantitative flow cytometry is critical to your cellular analysis workflows.

Key Benefits

  • Gentle cell handling
  • Reduced hands-on time
  • Scalability and versatility
  • Improved data quality

Learn more 

Why Change?

Traditional centrifugation methods have long been the cornerstone of cellular analysis, but they come with significant drawbacks. These methods subject cells to substantial mechanical stress, leading to cell loss, reduced viability, and compromised data quality. As research demands grow more rigorous, the need for precision, accuracy, and reproducibility in cellular analysis becomes paramount. The question isn’t just about improving your current workflow—it’s about revolutionizing it. Laminar wash technology offers a groundbreaking alternative that addresses the limitations of centrifugation, providing a path to more reliable, consistent, and high-quality results.

Why Now?

In today’s fast-evolving research landscape, the margin for error is shrinking, and the pressure to deliver fast, accurate, and reproducible results is intensifying. Whether you’re involved in drug discovery, cell therapy, or cellular expansion, the quality of your data directly impacts the success of your research. Traditional methods are not only time-consuming but also prone to variability and human error, which can skew results and delay advancements.

Now is the time to embrace a technology that enhances your workflow, reduces hands-on time, and ensures the highest standards of data integrity. With laminar wash technology, you can meet the increasing demands of modern research and stay ahead in your field.

Laminar wash resulted in a two-fold increase in cell retention, at the lower cell inputs, compared to traditional centrifugation protocols. This was important for working with rare and sensitive cell types like T cells, where cell loss can be a significant issue.

Dan Imhoff
Tune Therapeutics

Why Curiox Laminar Wash Technology?

Laminar wash technology is a game-changer in the realm of cellular analysis. By utilizing proprietary laminar flow technology, it gently washes suspension cells with unparalleled precision. This process not only preserves cell integrity and viability, but also yields consistently reliable results with higher cell retention, increased resolution, and superior data quality. For researchers who rely on quantitative flow cytometry, this technology is indispensable.

One of the most compelling features of the laminar wash technology is its ability to significantly reduce sample handling and hands-on time. By eliminating the need for centrifugation and the associated steps of aspirating and flicking, researchers can save up to 70-90% of their cell processing time. This efficiency doesn’t just save time—it minimizes the potential for human error, enhancing experiment reproducibility and ensuring that every sample undergoes identical processing.

Laminar wash technology also excels in supporting rare and precious cell types, providing improved resolution and viability for even the most delicate samples. Its scalability and versatility make it suitable for various laboratory sizes, offering 24-, 48-, and 96-well throughputs to meet different research needs. Whether you’re working in drug discovery, cell therapy, or any other field reliant on cellular analysis, laminar wash technology integrates seamlessly into your workflow, offering an elegant, fast, and cost-effective alternative to traditional centrifugation methods.

By adopting laminar wash technology, you’re not just upgrading your cell processing techniques—you’re setting a new standard for accuracy, efficiency, and data quality in cellular analysis. This is the future of cell washing: gentle, reliable, and designed to deliver deeper insights and faster advancements across all areas of research.

Key Benefits

Gentle Cell
Handling

Preserves cell integrity by using laminar flow instead of high-stress centrifugation—removes supernatants gently.

Reduces Hands-On Time

Eliminates multiple manual steps including aspirating and flicking, saving up to 70-90% in cell processing time.

Scalability and Versatility

Supports various throughput needs, from 24- to 96-wells, making it ideal for different laboratory sizes and research needs.

Improves Data
Quality

Provides consistently reliable results with higher cell retention and reduces sample variability.

Applications

Research areas reliant on cellular analysis that can benefit by laminar wash technology are:
  • Drug discovery
  • Cell therapy
  • Animal model studies
  • Apoptosis
  • Biomarker identification and discovery
  • Cellular expansion success (during manufacturing)
Benefits that support the need researchers have for more accurate data, deeper insights and faster advancements include:
  • Ensuring higher cell viability by keeping cells un-stressed in their native state
  • Integrating with cell analysis workflows, particularly in combination with automated data analysis
  • Elegant, fast, and low cost alternative to centrifugation methods

Significant Savings Over Traditional Methods

Centrifuge Versus Laminar Wash Technology 

Compared to a centrifuge-driven workflow, Curiox laminar wash technology is simpler and faster.

 Improved Retention

Laminar washing delivers better cell retention and cleaner, clearer data increasing lymphocyte recovery up to 90.6% vs. 10.5% with centrifuge washing.

Better Cell Retention and Clearer Data

Laminar wash advances with neutrophils and monocytes retention for improved blood count.

Related Products

  • Venus System

  • Pluto System

Key Resources

Impact of Novel Curiox Laminar Wash on Nuclei Retention and Other Downstream Applications

Read More

White Paper—Immunophenotyping Rare Immune Cells with Laminar Wash AUTO System

Read More

Poster—PBMCs processed from whole blood with Laminar Wash-based methods yield fewer apoptotic cells than centrifugation

Read More

White Paper—Flow Cytometric HLA Crossmatch Workflow with the Curiox Laminar Wash HT2000

Read More

Curiox Laminar Wash Featured on Charles River Lab’s Eureka Science Blog

Read More

Developing a 43 color panel on Cytek Aurora using Laminar Wash for Sample Prep

Read More

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.

Name
Organization