Category: Flow Cytometry

Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction

READ NATURE PORTFOLIO PREPRINT Researchers at the University of Chicago used their Laminar Wash HT2000 system to safely prepare peripheral immune cells from COVID-19 patients with moderate and severe disease for flow cytometry in a biosafety cabinet. This preprint manuscript in a Nature family journal reveals how increased IL-6 and CCL2 in patients with severe […]

AUTO1000: Automate Your Cell Staining Workflow

The Curiox Laminar Wash AUTO 1000 System completely automates the staining and washing workflow, eliminating a major source of variability and enabling process standardization. The AUTO 1000 system offers several key benefits to research and shared resource laboratories in cell and gene therapy discovery and process development, antibody screening, flow core labs, and other applications that rely on cell-based assays.

Enabling Single-cell Multiomics and Cell Hashing in Studies with Limited Numbers of Cells

Now Watchinghttps://youtu.be/LagyuoWvELo Our October 19, 2021 webinar featured University of Gothenburg Associate Professor of Immunology Mats Bemark, Ph.D. and Curiox Biosystems Marketing & Content Manager, Geoffrey Feld, Ph.D. Dr. Bemark studies mucosal immunology, with particular focus on the gut and gut-related infections like cholera, and recently has been working on COVID-19 with human severe disease samples. His […]

Manufacturing Living Therapies

Enabling “next-generation” drugs through automation and standardization This article was first published on Charles River Laboratories Eureka Blog. Please support our partners at Charles River. Cell and gene therapy continues to drive biopharmaceutical investment and pipelines, despite COVID-related research and clinical trial disruptions. Last year, the global cell therapy market size was $7.8 billion, expanding annually […]

Nuclei Need Nurturing, Too

Laminar Wash™ benefits of automation and gentle cell-based sample preparation can also be extended to nuclei Analytical methods on individual cells provide an enormous amount of useful information. But not all tissue types lend themselves to preparing single cell suspensions necessary for flow cytometry or single-cell ‘omics analysis. Homogenization and dissociation of interconnected tissues such […]

Towards standardizing flow cytometry sample preparation protocols without centrifugation

Now Watchinghttps://youtu.be/NTTfiQiqhqE In this sponsored webinar by the flowcytometryUK society webinar, renowned flow cytometrist Derek Davies, Ph.D. of the Francis Crick Institute hosted a discussion featuring Curiox Applications Scientist Noma Ngwenya and Charles River Laboratories Principal Scientist III and Flow Cytometry Core Director Christoph Eberle, Ph.D.  They explored how Laminar Wash™ technology enhances sample preparation for flow cytometry by […]

A Missing Sample Prep Tool for Single-Cell Biology is Found

Gentle and semi-automated Laminar Wash™ technology removes background, debris, doublets, and dead time, extending single-cell ‘omics budgets. Single-cell ‘omics technologies are achieving a new paradigm in biology. As Eadweard Muybridge applied photography to settle the “unsupported transit” controversy surrounding the 19th century galloping horse, immunologists are utilizing single-cell transcriptomics (scRNA) to tease apart the heterogeneity […]