Surfaceome mapping of primary human heart cells with CellSurfer uncovers cardiomyocyte surface protein LSMEM2 and proteome dynamics in failing hearts

Luecke, L. B., Waas, M., Littrell, J., Wojtkiewicz, M., Castro, C., Burkovetskaya, M., Schuette, E. N., Buchberger, A. R., Churko, J. M., Chalise, U., Waknitz, M., Konfrst, S., Teuben, R., Morrissette-McAlmon, J., Mahr, C., Anderson, D. R., Boheler, K. R., & Gundry, R. L. (2023). Nature Cardiovascular Research, 2(1), 76–95. https://doi.org/10.1038/s44161-022-00200-y Cardiac cell surface proteins […]

AUTO1000: Automate Your Cell Staining Workflow

The Curiox Laminar Wash AUTO 1000 System completely automates the staining and washing workflow, eliminating a major source of variability and enabling process standardization. The AUTO 1000 system offers several key benefits to research and shared resource laboratories in cell and gene therapy discovery and process development, antibody screening, flow core labs, and other applications that rely on cell-based assays.

Enabling Single-cell Multiomics and Cell Hashing in Studies with Limited Numbers of Cells

Now Watchinghttps://youtu.be/LagyuoWvELo Our October 19, 2021 webinar featured University of Gothenburg Associate Professor of Immunology Mats Bemark, Ph.D. and Curiox Biosystems Marketing & Content Manager, Geoffrey Feld, Ph.D. Dr. Bemark studies mucosal immunology, with particular focus on the gut and gut-related infections like cholera, and recently has been working on COVID-19 with human severe disease samples. His […]

Centrifuge-Less Automation of Suspension Cell Sample Preparation

Now Watchinghttps://www.youtube.com/watch?v=wkxcKl8DNMc In our webinar from February 24, 2021, Curiox Applications Scientist Ann Wang and Peak Analysis and Automation (PAA) Technical Director Dr. Malcolm Crook discussed how Laminar Wash™ technology can readily automate sample preparation, sans centrifuge. Ann starts things off, introducing Laminar Wash technology and Curiox solutions for automated cell prep. She also addressed questions in the Q&A with data. Highlights include: […]

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries

Now Watching Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries  Elijah W. Chen*1, Chyan Ying Ke*2,3, Joanna Brzostek*1, Nicholas R. J. Gascoigne1, Vasily Rybakin1,41Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Singapore Immunology Network, A*STAR, 3Curiox Biosystems, 4Department of Immunobiology, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven * These authors […]

Development of a 43 color panel for the characterization of conventional and unconventional T‐cell subsets, B cells, NK cells, monocytes, dendritic cells, and innate …

Sahir, F., Mateo, J. M., Steinhoff, M., & Siveen, K. S. (2020). Cytometry Part A, 105(5), 404–410. https://doi.org/10.1002/cyto.a.24288 Although many flow cytometers can analyze 30–50 parameters, it is still challenging to develop a 40+ color panel for the phenotyping of immune cells using fluorochrome conjugated antibodies due to limitations in the availability of spectrally unique […]