Thank you for visiting Curiox at SLAS and engaging with our centrifuge-free automation demonstrations! This page brings together the data, examples, and context automation teams most often asked for when evaluating whether centrifugation can be replaced by your liquid handler.
Use the resources below to assess function, performance, and deployment options.






At the core of C-FREE™ technology is Pluto Code, a script library that enables centrifuge-free washing on standard liquid-handling platforms. Instead of relying on centrifugation, it uses controlled pipetting motions to precisely regulate fluid flow around cells, enabling effective liquid exchange without mechanical force.
By eliminating the need for centrifugation, Pluto Code standardizes the wash step across workflows and instruments without requiring additional hardware integrations.
Centrifuge-free washing is easy to implement in your automated workflows and scalable across large, multi-site organizations. Automation teams typically deploy the C-FREE approach in one of two ways:
Hamilton · Beckman Coulter · Tecan · Opentrons
Pluto Code can be implemented on supported liquid-handling platforms, allowing teams to standardize wash steps without changing their core automation infrastructure.
The Pluto Workstation is an integrated high-throughput platform incorporating centrifuge-free washing. It is designed for labs that prefer a dedicated system for standardized, scalable sample preparation workflows.
These resources help teams assess the performance of C-FREE washing versus manual centrifugation as well as the standardization and scalability of centrifuge-free washing in automated workflows.
Pluto Code-Enabled Centrifuge-Free Automation: Toward a Universal Standard for Gentle Wash
Validated 384-Well Centrifuge-Free Washing for High-Throughput Cell Prep
“The staining process from start to finish is fully integrated. If you already have a liquid handler, you continue to use your own system. It eliminates multiple pieces of equipment and simplifies the overall schedule for end-to-end automation.”
“This centrifuge-free workflow allows us to scale and generate reproducible data across larger datasets. We can spend more time analyzing the data and thinking about experimental design, while leaving the execution to the Curiox/Opentrons system.”
From the compact and intuitive Pluto ALPHA to fully automated Pluto Workstation, our lineup works with your existing labware and scales with your needs. And with Pluto Code, you can even automate prep on the robots you already own.
If you’re evaluating a specific workflow or have technical questions, reach out to your Curiox sales rep or contact us at sales@curiox.com.