Large scale cytokine profiling uncovers elevated IL12‑p70 and IL‑17A in severe pediatric acute respiratory distress syndrome

Publication Year: 2021 Read Scientific Reports

Investigators in Singapore utilized Curiox’s DropArray (LT210) multiplex immunoassay system to profile 45 cytokines, chemokines, and growth factors in children with severe and non-severe PARDS. This revealed a differential immunological signature correlating with early and late disease, shedding light on PARDs pathophysiology.

Judith Ju Ming Wong, Herng Lee Tan, Jieliang Zhou, Jan Hau Lee, Jing Yao Leong, Joo Guan Yeo, & Yie Hou Lee. Large scale cytokine profiling uncovers elevated IL12‑p70 and IL‑17A in severe pediatric acute respiratory distress syndrome. Scientific Reports. 2021; 11:14158