Ex vivo T cell differentiation in adoptive immunotherapy manufacturing: Critical process parameters and analytical technologies
Sixun Chen, Tan Dai Nguyen, Kang-Zheng Lee, Dan Liu, https://doi.org/10.1016/j.biotechadv.2024.108434 Adoptive immunotherapy shows great promise as a treatment for cancer and other diseases. Recent evidence suggests that the therapeutic efficacy of these cell-based therapies can be enhanced by the enrichment of less-differentiated T cell subpopulations in the therapeutic product, giving rise to a need for […]
Meet Us at GLIIFCA 33rd Annual Meeting!
Curiox is honored to be a sponsor of this year’s GLIIFCA conference. GLIIFCA XXXIII will be September 12-14, 2024 at the Marriott Cincinnati Rivercenter in Covington, KY. We are pleased to announce that our esteemed colleague, Nadiezda Fernandez Oropeza, PhD will be presenting our latest technological advancements. This session presents an excellent opportunity to gain insights into the innovations […]
POSTER—Replacing the centrifuge to increase T-cell recovery and generate consistent data: The Laminar Wash™ approach
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Profiling Circulating T cells and Tumor Landscape for Predicting Responses to PD-1 blockade in Patients with Non-Small Cell Lung Cancer
Dutta, N. (2024, September 5). https://gupea.ub.gu.se/handle/2077/81804 Immune checkpoint blockade (ICB) has significantly improved outcomes in non-small cell lung cancer (NSCLC), yet only a subset of patients achieves durable responses. This underscores the need for effective methods to assess ICB efficacy. This thesis investigates the response to PD-1 blockade in NSCLC patients across stages I to […]
POSTER—2024 – An Automated, Centrifuge-Less Workflow for Cell Staining and Washing of Flow and Mass Cytometry Samples
Flow cytometry is widely used in research and clinical settings, but automating sample preparation remains a challenge due to the high cost and large footprint of traditional liquid handling systems. Curiox’s Centrifuge-Less (C-FREE™) technology offers a smaller, more cost-effective solution by using laminar flow to wash and stain cells in 96-well plates without centrifugation. C-FREE™ […]
Discover the Future of Flow Cytometry at SoCal Flow Sumit 2024
We are excited to return to the SoCal Flow Summit, happening on April 8-9, 2024, in Irvine, California! Join us on April 8th at 2:35 PM for a 15-minute presentation by Amelia McGuire, “Automating Flow Cytometry with Curiox Biosystems” She will unveil how Curiox Biosystems is revolutionizing sample preparation with our cutting-edge automation solutions. Discover […]
Breathe Easy with Better Models
Now Watching Research for Activating Macrophages and Dendritic Cells with Nanomedicine in Lung Carcinoma https://youtu.be/wljKOIcYsUM Macrophages can mediate phagocytosis of cancer cells and cytotoxic tumor killing, and engage in effective bidirectional interactions with components of the innate and adaptive immune system. Given the continuous recruitment of myelomonocytic cells into tumor tissues, macrophages are candidates for […]
Meet Us at SEFCIG 2024
Curiox Biosystems is thrilled to announce our participation in SEFCIG 2024, the Southeast Flow Cytometry Interest Group meeting, taking place from March 14-15, 2024, in Memphis, TN. This event is a key gathering for flow cytometry professionals and researchers, providing a platform to explore the latest developments, share knowledge, and engage with experts in the […]
Reinvigoration of Progenitor-Exhausted CD8 T Cells by anti-CTLA-4 Contributes to the Sustained Activity of Combination Checkpoint Blockade
Wang, Kevin and Coutifaris, Paulina and Brocks, David and Solis, Sabrina and Han, Nicholas and Manne, Sasikanth and Kiner, Evgeny and Sachar, Chirag and George, Sangeeth and Yan, Patrick and Kier, Melanie W. and Laughlin, Amy I. and Kothari, Shawn and Giles, Josephine R. and Mathew, Divij and Ghinnagow, Rheem and Alanio, Cecile and Flowers, […]
Critical Quality Metrics in Cell Sample Prep for Cell & Gene Therapy Bioanalytics
Now Watchinghttps://youtu.be/vEgp_FSQHF8 In this panel discussion, Virginia Litwin, Ph.D. (CRL), Christoph Eberle, MICR, FRSPH (CRL), Mahwish Natalia, MA, Ph.D. (Takeda Oncology), and Melvin Lye, MBA (Curiox Biosystems) discuss the role of partnerships between early- and late-stream analytical assay developers. While tackling unique challenges in validating flow cytometric methods for Chimeric Antigen Receptor (CAR) T cells, […]