Defining the bone marrow atlas with high-dimensional biology via a novel CITE-seq workflow

Now Watchinghttps://youtu.be/hD4OV9vf-Ak Single-cell multimodal approaches and machine learning are transforming analysis of the human hematopoietic progenitor compartment. Cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) enables coupled surface protein and transcriptome profiling, revealing genomic programs underlying progenitor states. This webinar will present groundbreaking work establishing a high-resolution human bone marrow single-cell atlas using paired […]

An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors

Zhang, X., Song, B., Carlino, M. J., Li, G., Ferchen, K., Chen, M., Thompson, E. N., Kain, B. N., Schnell, D., Thakkar, K., Kouril, M., Jin, K., Hay, S. B., Sen, S., Bernardicius, D., Ma, S., Bennett, S. N., Croteau, J., Salvatori, O., . . . Grimes, H. L. (2024). Nature Immunology, 25(4), 703–715. https://doi.org/10.1038/s41590-024-01782-4 […]