Profiling Circulating T cells and Tumor Landscape for Predicting Responses to PD-1 blockade in Patients with Non-Small Cell Lung Cancer
Dutta, N. (2024, September 5). https://gupea.ub.gu.se/handle/2077/81804 Immune checkpoint blockade (ICB) has significantly improved outcomes in non-small cell lung cancer (NSCLC), yet only a subset of patients achieves durable responses. This underscores the need for effective methods to assess ICB efficacy. This thesis investigates the response to PD-1 blockade in NSCLC patients across stages I to […]
Getting to the Heart of the Matter: Novel Analytical Technologies Provide a New Perspective on a Complex Organ
Now Watchinghttps://www.youtube.com/watch?v=R-YT0iVN86c The heart is a 380-million-year-old organ, yet we do not have a complete understanding of the molecular landscape in the normal human adult heart. Of the many molecule classes present in the heart, we are especially lacking in our understanding of the cell surface proteins present on different cell types in the heart. […]