POSTER—2025 – Evaluating the Curiox C-FREE Pluto System for Whole Blood Immunophenotyping Sample Processing
Flow cytometry remains a critical tool for immunological research and diagnostics, yet traditional manual workflows can be labor-intensive and inconsistent. The Curiox C-FREE Pluto System (Pluto) introduces a fully-automated workflow solution, including antibody cocktailing, seamlessly integrating with conventional protocols without requiring adaptation. Pluto incorporates gentle washing of samples as opposed to harsh centrifugal forces with […]
Defining the bone marrow atlas with high-dimensional biology via a novel CITE-seq workflow
Now Watchinghttps://youtu.be/hD4OV9vf-Ak Single-cell multimodal approaches and machine learning are transforming analysis of the human hematopoietic progenitor compartment. Cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) enables coupled surface protein and transcriptome profiling, revealing genomic programs underlying progenitor states. This webinar will present groundbreaking work establishing a high-resolution human bone marrow single-cell atlas using paired […]
MetroFlow 2024 Annual Meeting
We’re proud to be one of the sponsors for MetroFlow 2024 annual meeting. The meeting will be held at The Kean University in Union, NJ on November 14th, 2024. Check the event website for more information including agenda and speaker info. We hope to see you there! Subscribe to our newsletter Get updates about upcoming webinar technical […]
Conference: Curiox will be at the 39th International Clinical Cytometry Society (ICCS)
You are cordially invited to attend ICCS 2024, the 39th Annual International Clinical Cytometry Meeting & Course. Please join us from October 4-8, 2024. The ICCS Annual Course will take place at the Westin Seattle Hotel. Stop by Booth 300 to explore how our advanced solutions can transform your workflows with efficiency and precision.Whether you’re interested […]
Ex vivo T cell differentiation in adoptive immunotherapy manufacturing: Critical process parameters and analytical technologies
Sixun Chen, Tan Dai Nguyen, Kang-Zheng Lee, Dan Liu, https://doi.org/10.1016/j.biotechadv.2024.108434 Adoptive immunotherapy shows great promise as a treatment for cancer and other diseases. Recent evidence suggests that the therapeutic efficacy of these cell-based therapies can be enhanced by the enrichment of less-differentiated T cell subpopulations in the therapeutic product, giving rise to a need for […]
Meet Us at GLIIFCA 33rd Annual Meeting!
Curiox is honored to be a sponsor of this year’s GLIIFCA conference. GLIIFCA XXXIII will be September 12-14, 2024 at the Marriott Cincinnati Rivercenter in Covington, KY. We are pleased to announce that our esteemed colleague, Nadiezda Fernandez Oropeza, PhD will be presenting our latest technological advancements. This session presents an excellent opportunity to gain insights into the innovations […]
Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells
Wang et al., 2024, Cancer Cell 42, 1–16 In the new era of cancer treatment, immunotherapy has become a revolutionary therapeutic approach. Particularly, immune checkpoint inhibitors such as anti-PD-1 and anti-CTLA-4 antibodies have significantly improved the survival rates of patients with various types of cancer. Immune checkpoint inhibitors enhance the body’s immune response to cancer […]
Profiling Circulating T cells and Tumor Landscape for Predicting Responses to PD-1 blockade in Patients with Non-Small Cell Lung Cancer
Dutta, N. (2024, September 5). https://gupea.ub.gu.se/handle/2077/81804 Immune checkpoint blockade (ICB) has significantly improved outcomes in non-small cell lung cancer (NSCLC), yet only a subset of patients achieves durable responses. This underscores the need for effective methods to assess ICB efficacy. This thesis investigates the response to PD-1 blockade in NSCLC patients across stages I to […]
POSTER—2024 – An Automated, Centrifuge-Less Workflow for Cell Staining and Washing of Flow and Mass Cytometry Samples
Flow cytometry is widely used in research and clinical settings, but automating sample preparation remains a challenge due to the high cost and large footprint of traditional liquid handling systems. Curiox’s Centrifuge-Less (C-FREE™) technology offers a smaller, more cost-effective solution by using laminar flow to wash and stain cells in 96-well plates without centrifugation. C-FREE™ […]
Resistance of CAR-T Immunotherapy For Hematological Cancers
Now Watchinghttps://youtu.be/-09n_Qib-co Explore the advancements in CAR-T immunotherapy for relapsed/refractory B cell lymphomas and leukemia in an exclusive webcast featuring Dr. Marco Ruella, a distinguished expert in cellular immunotherapies. Dr. Ruella’s presentation will showcase innovative research focusing on enhancing CAR-T therapy by uncovering tumor evasion mechanisms and addressing challenges in CAR-T cell dysfunction and the […]