Automated flow cytometry staining protocol video
Now Watching This video demonstrates the AUTO1000 accomplishing an automated standard cell staining protocol to prepare samples for analysis by flow cytometry. The video is set at 40X speed. Notice how fast the Laminar Wash step is executed, relative to the “rate limiting steps” of automatic pipetting, as well as how clear those wells are after washing! Curiox’s […]
Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways
READ FRONTIERS IN IMMUNOLOGY Stewart A., Ng JC-F, Wallis G, et al. Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways. Front. Immunol. 2021;12:602539. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
How to wash away barriers to therapeutic cancer vaccine development
Developing neoantigen-based cancer vaccines necessitates comprehensive cellular characterization for iterative therapeutic improvement, which Laminar Wash™ systems may facilitate at multiple steps. Vaccines are probably the second-most effective advancement in the annals of human medicine, after sanitation. Most of us recognize the value of vaccines in infectious disease. Yet, swept under the rug amongst the COVID-19 global pandemic is another form of immune-boosting injection combating a terrible […]
The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut
READ MICROBIOME Arnold JW, Roach J, Fabela S, et al. The pleiotropic effects of prebiotic galacto-oligosaccharides on the aging gut. Microbiome. 2021;9(1):31 Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
CTLA-4 blockade drives loss of Treg stability in glycolysis-low tumour
READ NATURE Zappasodi R, Serganova I, Cohen IJ, et al. CTLA-4 blockade drives loss of T reg stability in glycolysis-low tumours. Nature. 2021 Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Centrifuge-Less Automation of Suspension Cell Sample Preparation
Now Watchinghttps://www.youtube.com/watch?v=wkxcKl8DNMc In our webinar from February 24, 2021, Curiox Applications Scientist Ann Wang and Peak Analysis and Automation (PAA) Technical Director Dr. Malcolm Crook discussed how Laminar Wash™ technology can readily automate sample preparation, sans centrifuge. Ann starts things off, introducing Laminar Wash technology and Curiox solutions for automated cell prep. She also addressed questions in the Q&A with data. Highlights include: […]
Laminar Wash Technology: an Overview
Now Watchinghttps://www.youtube.com/watch?v=eoFLbXX2Efc This animation provides an overview of why Laminar Wash represents a disruptive, next-generation technology for optimal cell-containing sample preparation, including what it replaces (centrifuge-reliant methods), how it works (unique plate design plus laminar flow fluidics), and why it is key to bringing sample prep into the 21st century. Highlights include: Introduction to cell washing (0:05) […]
Overcoming challenging cell analysis with next-generation sample prep technology
Laminar wash technology enables researchers to perform routine, thorough, and gentle cell washes, especially for troublesome and low cell count populations. Researchers are delivering on the promise of genomic and cell biology to cure individual cancers and correct genetic disorders at breakneck speed. Feeding this acceleration has been unprecedented advances in cellular analysis—characterizing and selecting […]
Laminar Wash Technology for Sample Preparation – How it Works
Now Watchinghttps://www.youtube.com/watch?v=2AF8nyanzc4 Laminar Wash technology represents a completely new way to approach cell washing and sample preparation. The system comprises two essential components: a unique plate design and fluidics that generate laminar flow across the sample. This animation covers “how it works” as part of our longer video on Laminar Wash technology. Highlights include: The unique characteristics of the Laminar […]
Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
Now Watching Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries Elijah W. Chen*1, Chyan Ying Ke*2,3, Joanna Brzostek*1, Nicholas R. J. Gascoigne1, Vasily Rybakin1,41Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Singapore Immunology Network, A*STAR, 3Curiox Biosystems, 4Department of Immunobiology, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven * These authors […]