Bridging the Automation Gap in Biotech and Life Sciences Research
By Mahrukh (Mahi) Banday, EVP/GM Marketing, Product, Operations at Curiox Biosystems March 6, 2025 The Critical Need for Automation in Life Sciences Biotech and life sciences research are evolving at an unprecedented pace, with breakthroughs in genomics, immunology, and cell therapy driving the need for high-throughput, high-precision workflows. Yet, one bottleneck remains persistent—cell sample preparation. […]
Ex vivo T cell differentiation in adoptive immunotherapy manufacturing: Critical process parameters and analytical technologies
Sixun Chen, Tan Dai Nguyen, Kang-Zheng Lee, Dan Liu, https://doi.org/10.1016/j.biotechadv.2024.108434 Adoptive immunotherapy shows great promise as a treatment for cancer and other diseases. Recent evidence suggests that the therapeutic efficacy of these cell-based therapies can be enhanced by the enrichment of less-differentiated T cell subpopulations in the therapeutic product, giving rise to a need for […]
POSTER—Replacing the centrifuge to increase T-cell recovery and generate consistent data: The Laminar Wash™ approach
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Combating Burnout in Life Science Professionals: The Role of Streamlining and Automation
Burnout has become a widely discussed issue in various aspects of our lives, from our careers to personal well-being. The World Health Organization defines burnout as an “occupational phenomenon,” resulting from prolonged workplace stress left unresolved. While the immediate impact of the COVID-19 pandemic has brought heightened awareness to burnout, it has long been a […]
Automated Characterization Method for Validation of Epigenomic Editors in T Cells
Now Watchinghttps://youtu.be/-oRv-U2VMHg To view the transcript click here. Robust characterization methods are important analytical tools for phenotypic characterization in cell and gene therapy. For high-parameter flow cytometry methods, sample preparation is a highly complex and mostly manual procedure. Traditional flow cytometry methods are limited in throughput and resource intensive, which make them suboptimal for discovery screening […]
Future-Proofing Single Cell Applications
Now Watchinghttps://youtu.be/wL2tsRsL9TA Technology has evolved from those early days of batching thousands of cells together to decrypt the millions of base pairs that make up genetic information. Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq), brings together surface protein phenotyping (similar to flow cytometry) and single-cell RNA sequencing (scRNA-seq). This is achieved by using […]
An Invention of Admiration
“When I met Ana, I knew: I loved her to the point of invention.” – The Clean House, Sarah Ruhl Why Laminar Wash Our Laminar Wash™ technology is a declaration of love and admiration to all of the amazing, status quo breaking, visionaries that won’t stand to wait for the future to come to them; […]
The Direct Reading Grid – How it Works
Now Watchinghttps://youtu.be/_wdesbdI5ZkIn this video provides walk-throughs on pairing the Direct Reading Grid (DRG) with the Laminar Wash™ (LW) Plate to create the DRG & LW Plate Unit as well as pipetting, handling, transferring, and Big Bear Vortexing with the DRG and LW Plate Unit.
Getting to the Heart of the Matter: Novel Analytical Technologies Provide a New Perspective on a Complex Organ
Now Watchinghttps://www.youtube.com/watch?v=R-YT0iVN86c The heart is a 380-million-year-old organ, yet we do not have a complete understanding of the molecular landscape in the normal human adult heart. Of the many molecule classes present in the heart, we are especially lacking in our understanding of the cell surface proteins present on different cell types in the heart. […]
Undoing Automation Roadblocks with the AUTO 1000
Now Watchinghttps://www.youtube.com/watch?v=mss00mrNLVk Automation is the key to solving “road blocks” of all kinds. Automated processes minimize variability, eliminate error, and increase throughput. Whether it is the toll road systems or laboratory workflows such as sample preparation, efficient and user-friendly automation has many benefits: Time Savings Reproducibility Shorten Turnaround Time Free Up Personnel Drive Standardization Unlike […]