Manufacturing Living Therapies

Enabling “next-generation” drugs through automation and standardization This article was first published on Charles River Laboratories Eureka Blog. Please support our partners at Charles River. Cell and gene therapy continues to drive biopharmaceutical investment and pipelines, despite COVID-related research and clinical trial disruptions. Last year, the global cell therapy market size was $7.8 billion, expanding annually […]
Laminar Wash HT2000 plus Buffer Exchanger Virtual Demonstration

Now Watchinghttps://www.youtube.com/watch?v=v4TGUjS_bDg This video demonstrates the daily operation and utility of the Laminar WashTM HT2000 system, outfitted with a buffer exchanger to facilitate automation. Comprised of a prepriatary 96-well “wall-less” plate and a robotic fluidics instrument, the HT2000 is the ideal solution to the reproducible and hands-free preparation of suspension cell samples for flow cytometry and single-cell ‘omics applications. Additionally, […]
Integration of Curiox Laminar Wash HT2000 with Thermo Scientific Orbitor and PAA S-Lab Plate Handlers

Now Watchinghttps://www.youtube.com/watch?v=WEsZ9VpO2eo In this video, the utility of the Laminar Wash HT2000 system for automating cell suspension sample prep workflows is demonstrated. The HT2000 instrument is compatible with a range of robotic plate mover systems to facilitate antibody screening, cell and gene therapy analytical and process development, and other high throughput applications where hands-off time, reproducibility, and […]
Centrifuge vs Laminar Wash HT2000 Time-Motion Study

Now Watchinghttps://www.youtube.com/watch?v=MeR1PdvoR7g This time-motion study aims to assess and compare features of two different cell sample preparation methods, namely the conventional centrifugation method and the centrifuge-less Laminar Wash™ method. Traits such as the hands-on and walk-away times, as well as the complexity of movements required to interact with the instruments were evaluated. Materials and Methods Equivalent […]
Centrifuge-Less Automation of Suspension Cell Sample Preparation

Now Watchinghttps://www.youtube.com/watch?v=wkxcKl8DNMc In our webinar from February 24, 2021, Curiox Applications Scientist Ann Wang and Peak Analysis and Automation (PAA) Technical Director Dr. Malcolm Crook discussed how Laminar Wash™ technology can readily automate sample preparation, sans centrifuge. Ann starts things off, introducing Laminar Wash technology and Curiox solutions for automated cell prep. She also addressed questions in the Q&A with data. Highlights include: […]
Automating cell prep with Laminar Wash–SLAS 2021

Now Watchinghttps://www.youtube.com/watch?v=bisHv1x1lkE Description Laminar Wash technology offers a centrifuge-less sample preparation method that can be readily automated. Our presentation at the Society for Laboratory Automation and Screening (SLAS) 2021 conference, Curiox Applications Scientist Ann Wang and Sales Manager Dr. Darren Warnick discussed cell prep automation. In the first part of the talk, Dr. Darren Warnick […]
Enhancing Cell Recovery and Debris Removal for Frozen Lymphocytes for Single Cell Multi-Omics

Now Watchinghttps://www.youtube.com/watch?v=aJQahE_Bf5I Description In this webinar, Dr. Bertrand Yeung and Dr. Antonino Montalbano present their experience using Laminar Wash technology for single-cell genomics and proteogenomics. BioLegend manufactures CITE-Seq assay kits (TotalSeq). A co-developer of the method and Curiox Business Development Director (formally of BioLegend), Dr. Bertrand Yeung explains how extensive cell washing is critical to study […]
White Paper—Handling Frozen Lymphocytes for HLA Flow Crossmatches Using Laminar Flow
Now Watchinghttps://www.youtube.com/watch?v=a-Hi4s19lQc Description Blanca Ponce-Ngo was the Transplant Immunology Lab Manager at Montefiore Medical Center in NY. Her webinar focuses on three main topics related to the handling of frozen samples for HLA Crossmatching as follows: 1) Comprehensive transfer of a Flow Crossmatching Assay 2) Impact of using frozen samples required by the National Kidney […]
User Manual—Buffer Exchanger

Buffer Exchanger User Manual