Laminar Wash Technology for Sample Preparation – How it Works

Now Watchinghttps://www.youtube.com/watch?v=2AF8nyanzc4 Laminar Wash technology represents a completely new way to approach cell washing and sample preparation. The system comprises two essential components: a unique plate design and fluidics that generate laminar flow across the sample. This animation covers “how it works” as part of our longer video on Laminar Wash technology. Highlights include: The unique characteristics of the Laminar […]

The Curiox Case for Better Cell Analysis

Curiox Biosystems to Advance Next-Generation Cancer Cell Therapies Through Collaboration with Leading Cancer Researcher January 21, 2021 In, 1885, German biologist Wilhelm Roux took part of the brain from a chicken embryo and placed it in warm saline solution, keeping it alive for several days. Simple as the experiment was, it seeded the idea that […]

Developing a 43 color panel on Cytek Aurora using Laminar Wash for Sample Prep

The advent of modern flow cytometers and flow cytometric methods has accelerated researchers’ ability to enhance the resolution of samples analyzed. Within a span of 20 years, flow cytometry panels have ballooned from a handful of channels to well over 40. The theoretical limit of flow panels now lies not in the available fluorophores or […]

Laminar Wash™ Technology Enabled Accurate Identification of Tumor Infiltrating Lymphocyte (TIL) Population

Immunotherapy, a treatment that harnesses the patients’ own immune systems to fight off cancer, is revolutionizing cancer treatment. Since the original success in melanoma, significant advances have led to novel immunotherapeutic approaches for treatment of various types of cancer, with a large number of clinical trials being currently underway. The successful anti-tumor immune response is […]

Washing Whole Blood Without a Centrifuge – Human and Mouse

Lysing and washing red blood cells using traditional microtiter plates or tubes may result in significant cell loss and damage. There is now a better way to lyse RBCs while achieving clean antibody staining and lysis as good as or better than traditional methods. The new Laminar Wash™ System offers centrifuge-less blood lysis and leukocyte […]

Single Cell Genomics Workflow with Laminar Wash (LW) in Biosafety Cabinet

Now Watchinghttps://www.youtube.com/watch?v=3bMAZ9cP75g Description Single cell genomics provide valuable information on the profiles and differences between individual cells from a heterogenous cell population, such as immune profiling of tumor microenvironments. Preparation of single cell suspensions for single cell genomic applications is crucial to obtaining high quality sequencing data. Factors such as poor cell retention and contamination […]

Preparation of Anti-Evaporation Lid

Now Watchinghttps://www.youtube.com/watch?v=hXtr0qFrqe4 Description This video describes how to set up the anti-evaporation lid for a DropArray plate used in a miniaturized multiplex bead immunoassay. In order to keep the small volume droplet from evaporating, a humidified environment is created by using the anti-evaporation lid.

Laminar Wash MINI1000 Setup and Workflow in Biosafety Cabinet

Now Watchinghttps://www.youtube.com/watch?v=wbZIFLzIwEc Description This video offers a detailed guide to using and maintaining the Laminar Wash MINI 1000 System for flow cytometry sample preparation. As demonstrated by our scientist in the video, setting up of the Laminar Wash MINI 1000 is straightforward, including pre-programmed priming steps. The Laminar Wash MINI 1000 System can be easily […]

Improved Cell Recovery by Skipping Centrifugation

Now Watchinghttps://www.youtube.com/watch?v=NJearwAfTwc Description Laminar Wash technology offers a centrifuge-less sample preparation method, which gently and continuously washes the cells in your samples. By eliminating centrifugation, sample preparation no longer subjects the cells to mechanical stress. This leads to better cell retention and produces higher quality data. In the first part of the webinar, watch how […]

Enhancing Cell Recovery and Debris Removal for Frozen Lymphocytes for Single Cell Multi-Omics

Now Watchinghttps://www.youtube.com/watch?v=aJQahE_Bf5I Description In this webinar, Dr. Bertrand Yeung and Dr. Antonino Montalbano present their experience using Laminar Wash technology for single-cell genomics and proteogenomics. BioLegend manufactures CITE-Seq assay kits (TotalSeq). A co-developer of the method and Curiox Business Development Director (formally of BioLegend), Dr. Bertrand Yeung explains how extensive cell washing is critical to study […]