Automated Characterization Method for Validation of Epigenomic Editors in T Cells
Now Watchinghttps://youtu.be/-oRv-U2VMHg To view the transcript click here. Robust characterization methods are important analytical tools for phenotypic characterization in cell and gene therapy. For high-parameter flow cytometry methods, sample preparation is a highly complex and mostly manual procedure. Traditional flow cytometry methods are limited in throughput and resource intensive, which make them suboptimal for discovery screening […]
Critical Quality Metrics in Cell Sample Prep for Cell & Gene Therapy Bioanalytics
Now Watchinghttps://youtu.be/vEgp_FSQHF8 In this panel discussion, Virginia Litwin, Ph.D. (CRL), Christoph Eberle, MICR, FRSPH (CRL), Mahwish Natalia, MA, Ph.D. (Takeda Oncology), and Melvin Lye, MBA (Curiox Biosystems) discuss the role of partnerships between early- and late-stream analytical assay developers. While tackling unique challenges in validating flow cytometric methods for Chimeric Antigen Receptor (CAR) T cells, […]
Could Debris Be Masking Your True Results
Now Watchinghttps://www.youtube.com/watch?v=TlQaihGArto Sample preparation is the stage that can make or break an assay’s performance. Preserving the natural state of samples without having to sacrifice population size can be the difference between innovation and stagnation. Now more than ever, we need dependable, reproducible results that don’t require a lab magician. With Laminar Wash, we can […]
Automating Cell Therapy Product: Constraints and Product Qualification for Fit-to-Process
Now Watchinghttps://www.youtube.com/watch?v=s-ptVJc2HpU When cells matter, it is key to prioritize their care at every stage. Clear resolution and retention of rare cell populations proves to be an issue in cell therapy processing utilizing traditional centrifugation methods. Automated, reproducible sample prep that does not rely on manual handling is the missing piece to saving precious samples, […]
How to wash away barriers to therapeutic cancer vaccine development
Developing neoantigen-based cancer vaccines necessitates comprehensive cellular characterization for iterative therapeutic improvement, which Laminar Wash™ systems may facilitate at multiple steps. Vaccines are probably the second-most effective advancement in the annals of human medicine, after sanitation. Most of us recognize the value of vaccines in infectious disease. Yet, swept under the rug amongst the COVID-19 global pandemic is another form of immune-boosting injection combating a terrible […]
Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
Now Watching Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries Elijah W. Chen*1, Chyan Ying Ke*2,3, Joanna Brzostek*1, Nicholas R. J. Gascoigne1, Vasily Rybakin1,41Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 2Singapore Immunology Network, A*STAR, 3Curiox Biosystems, 4Department of Immunobiology, Rega Institute for Medical Research, Katholieke Universiteit (KU) Leuven * These authors […]
Development of Centrifuge Independent Assays for Investigating T cell Signaling Pathways
Now Watchinghttps://www.youtube.com/watch?v=PtgqPNdoEeE Dr. Joanna Brzostek and Elijah Chen, of Dr. Nicholas Gascoigne’s Laboratory at National University of Singapore, describe their use of Laminar Wash technology (FKA DA-Cell) and T-cell activation, both looking at thymocytes and peripheral T-cells. In their work they encounter some very common problems, some of which are related to looking at the […]
Centrifuge-less Immuno-staining of Cells for Superior Viability, Recovery & Data
Now Watchinghttps://www.youtube.com/watch?v=kAUfEX1oQKY This webinar is presented by Sue Reynolds, Ph.D. Sue has extensive flow cytometry experience working in industry as a flow core manager, application scientist, field marketing and market development manager. Watch this webinar to learn about: Impacts of centrifugation on your cell samples and data Introduction to the working principles and products of […]
Centrifuge-less Immuno-staining of Cells for Superior Viability, Recovery & Data
Now Watching To see the full webinar, fill out the form below: https://www.youtube.com/watch?v=r9xM9rcCJCg
Probiotics-derived metabolite ameliorates skin allergy by promoting differentiation of FOXP3+ regulatory T cells
READ JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Kang H-J, Kim G-C, Lee C-G, et al. Probiotics-derived metabolite ameliorates skin allergy by promoting differentiation of FOXP3+ regulatory T cells. Journal of Allergy and Clinical Immunology. 2020. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the […]