Validating C-FREE™ Pluto Wash: Extending Laminar Wash™ Principles
WHITEPAPER From Laminar Wash™ to Pluto Wash™ — A Fluid‑Dynamics Validation Establishing Reliability of C-FREE™ Pluto Wash Technology through Proven Laminar Wash™ Principles: A Fluid Dynamics–Based Validation Automated. Centrifuge-less. Proven.This whitepaper demonstrates how the C-FREE™ Pluto Wash platform replicates the trusted Laminar Wash™ physics—delivering equivalent recovery, staining, and reproducibility in a fully automated workflow. See […]
Shared Principles, Consistent Results: Pluto Wash vs. Laminar Wash
By Melvin Lye, Senior Director of Scientific Affairs Introduction: Questioning a Long-Held Belief For decades, suspension cell workflows followed a rigid belief: centrifugation and pelleting were the only way to wash cells. This dogma shaped countless assays but also introduced variability, operator fatigue, and cell loss. Curiox challenged this in 2018 with Laminar Wash™ (LW), proving that […]
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics
Wang, M., Otto, C., Zapata, C. F., Dehlinger, A., Gallaccio, G., Diekmann, L., Niederschweiberer, M., Schindler, P., Körtvélyessy, P., Kunkel, D., Paul, F., Ruprecht, K., & Böttcher, C. (2025). Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics. iScience, 112383. https://doi.org/10.1016/j.isci.2025.112383 Ocrelizumab, an anti-CD20 antibody, depletes CD20+ B […]
Defining the bone marrow atlas with high-dimensional biology via a novel CITE-seq workflow
Now Watchinghttps://youtu.be/hD4OV9vf-Ak Single-cell multimodal approaches and machine learning are transforming analysis of the human hematopoietic progenitor compartment. Cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) enables coupled surface protein and transcriptome profiling, revealing genomic programs underlying progenitor states. This webinar will present groundbreaking work establishing a high-resolution human bone marrow single-cell atlas using paired […]
Immunopeptidomic MHC-I Profiling and Immunogenicity Testing Identifies Tcj2 as a New Chagas Disease mRNA Vaccine Candidate
Versteeg, L., Adhikari, R., Robinson, G., Lee, J., Wei, J., Islam, N., Keegan, B., Russell, W. K., Poveda, C., Villar, M. J., Jones, K., Bottazzi, M. E., Hotez, P., Tijhaar, E., & Pollet, J. (2024). PLoS Pathogens, 20(12), e1012764. https://doi.org/10.1371/journal.ppat.1012764 Trypanosoma cruzi is a protozoan parasite that causes Chagas disease. Globally 6 to 7 million […]
Brochure— HT2100 System
1-page flyer for the Curiox C-FREE Pluto System
POSTER—Replacing the centrifuge to increase T-cell recovery and generate consistent data: The Laminar Wash™ approach
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Higher debris removal–CRX-CRL_TIL-whitepaper_apr2021.pdf
https://staging.curiox.com/wp-content/uploads/2024/08/CRX-CRL_TIL-whitepaper_apr2021.pdf
Resistance of CAR-T Immunotherapy For Hematological Cancers
Now Watchinghttps://youtu.be/-09n_Qib-co Explore the advancements in CAR-T immunotherapy for relapsed/refractory B cell lymphomas and leukemia in an exclusive webcast featuring Dr. Marco Ruella, a distinguished expert in cellular immunotherapies. Dr. Ruella’s presentation will showcase innovative research focusing on enhancing CAR-T therapy by uncovering tumor evasion mechanisms and addressing challenges in CAR-T cell dysfunction and the […]
Resistance of CAR-T Immunotherapy For Hematological Cancers
Now Watchinghttps://youtu.be/-09n_Qib-co Explore the advancements in CAR-T immunotherapy for relapsed/refractory B cell lymphomas and leukemia in an exclusive webcast featuring Dr. Marco Ruella, a distinguished expert in cellular immunotherapies. Dr. Ruella’s presentation will showcase innovative research focusing on enhancing CAR-T therapy by uncovering tumor evasion mechanisms and addressing challenges in CAR-T cell dysfunction and the […]