POSTER 2025 – Gentle Media Exchange on an Automated Platform : High Cell Retention, Imaging-Compatible Workflow
Unlock the full poster to see how C-FREE™ Pluto platform transforms media exchange for imaging and flow cytometry workflows. This study demonstrates how gentle, centrifuge-free washing and programmable low-shear media exchange preserve cell integrity, boost retention, and deliver cleaner, more reliable data. Explore side-by-side comparisons with manual methods, insights from whole blood immunophenotyping, and performance […]
The Automation Conversation: What Pharma and Flow Cores Can Learn from Each Other
WEBINAR The Automation Conversation: What Pharma and Flow Cores Can Learn from Each Other Experts from AbbVie and GLIIFCA on modernizing flow cytometry workflows with automation “We had a bunch of disparate instruments and I had to carry plates from one instrument to another…The missing link was washing.” -Ryan Duggan AbbVie Get the Recording 60 […]
POSTER 2025 – Redefining Automated Cell Washing: Centrifuge-Less C-FREE™ Pluto Wash Configurations for Reliable Retention Across Diverse Cell Types
This poster summarizes a side-by-side comparison of manual vs. centrifuge-free workflows for whole blood immunophenotyping. Using automated antibody prep, staining, lysis, and programmable wash steps, the Pluto System achieved comparable cell retention, comparable population frequencies, and improved consistency across donors—all with reduced hands-on time.Download the full poster for detailed methods, figures, and analysis. Fill in […]
Shared Principles, Consistent Results: Pluto Wash vs. Laminar Wash
By Melvin Lye, Senior Director of Scientific Affairs Introduction: Questioning a Long-Held Belief For decades, suspension cell workflows followed a rigid belief: centrifugation and pelleting were the only way to wash cells. This dogma shaped countless assays but also introduced variability, operator fatigue, and cell loss. Curiox challenged this in 2018 with Laminar Wash™ (LW), proving that […]
POSTER 2025 – Reducing Operator-Dependent Variability in Immunophenotyping Through Automated Antibody Panel Preparation
Manual antibody cocktailing in high-dimensional flow cytometry often introduces user-to-user variability and consumes valuable hands-on time. This study evaluated an automated workflow using the Curiox C-FREE™ Pluto Workstation for antibody cocktailing, benchmarking it against manual methods across 10- and 24-color panels. Results showed that: Reproducibility improved: Replicate cocktail variation consistently stayed below 5%. Data quality […]
Pluto Code Secures First Global Biopharma Adoption, Redefining the Future of Centrifuge-Less Automation
Curiox Biosystems today announced the first commercial sale of Pluto Code — a licensing solution for centrifuge-less washing on liquid handlers — to a top-15 global biopharmaceutical company. The order marks a key milestone in the shift away from bulky, centrifuge-dependent automation toward software-driven simplicity. Industry Adoption The adoption by a leading global biopharma demonstrates […]
Pluto Automation: An Introduction to Centrifuge-Less Sample Prep
Automation shouldn’t take 12 months or cost $250k. Pluto reimagines what’s possible in the lab. This short overview introduces how Pluto delivers centrifuge-less cell washing and sample prep automation—making advanced automation accessible for every lab. https://youtu.be/2PxERlWVKkI Why Centrifuge-Less Matters for Cell Washing Traditional centrifuges can stress cells, slow down workflows, and introduce variability. Pluto replaces […]
Advancing Antibody Cocktail Solutions: Empowering CROs with Pluto Automation
By Melvin Lye, Senior Director of Scientific Affairs The preclinical CRO market is projected to reach USD 8.4 billion by 2030, driven by the rise in high-throughput studies and the demand for reproducible biomarker data in drug development. Yet, many Contract Research Organizations (CROs) still rely on manual pipetting for antibody cocktailing, creating bottlenecks that threaten […]
Automating Flow Cytometry Sample Prep: An ROI Calculation
Automating Flow Cytometry Sample Prep: An ROI Calculation Manual flow cytometry sample preparation is labor-intensive and costly, with multiple touchpoints for antibody cocktail prep, cell lysis, and staining. Each manual step adds labor cost, training time, and risk of error. Here we highlight the ROI of automated sample preparation, showing how Pluto Workstation reduces hands-on […]
Unlock Reproducibility in Flow Cytometry — Watch Now
Now Watching https://youtu.be/RTJU6rHmqTE Flow cytometry workflows often suffer from inconsistent results. Variability in cell preparation, preservation, staining, and analysis can compromise your data — and your research. In this short, must-watch video, Dr. Holden Maecker of Stanford HIMC reveals why these issues persist and how automation and standardization can deliver reproducible, high-quality flow cytometry data. […]