
Enabling high-throughput cell prep automation
Moving to 384-well formats increases throughput and reduces reagent use—but washing at this scale introduces real risks: sample loss, uneven retention, and assay variability. This application note evaluates C-FREE™ Pluto Wash’s ability to support reliable, reproducible washing at 384-well density, using a structured validation strategy that links fluidic performance to biologically relevant endpoints.
*384-Well throughput is expected to be available in the second half of 2026 for Pluto Code and Pluto Workstation.
12-15 min read • Immediate access
This application note presents a stepwise validation of C-FREE™ Pluto Wash at the 384-well format, benchmarked against established workflows:
Performance is assessed using both technical and biological models, allowing separation of fluidics from biological variability.
This application note is relevant for teams working on:
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