Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics
Wang, M., Otto, C., Zapata, C. F., Dehlinger, A., Gallaccio, G., Diekmann, L., Niederschweiberer, M., Schindler, P., Körtvélyessy, P., Kunkel, D., Paul, F., Ruprecht, K., & Böttcher, C. (2025). Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics. iScience, 112383. https://doi.org/10.1016/j.isci.2025.112383 Ocrelizumab, an anti-CD20 antibody, depletes CD20+ B […]
Longitudinal single-cell analysis of SARS-CoV-2-reactive B cells uncovers persistence of early-formed, antigen-specific clones
READ PUBMED When the body encounters a pathogen, such as a virus, the immune system develops an adaptive immune response through B-cell and T-cell responses to clear the infection and develop memory to this pathogen. This memory, often referred to as “immunological memory,” allows the body to respond more rapidly and specifically if it faces […]
Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways
READ FRONTIERS IN IMMUNOLOGY Stewart A., Ng JC-F, Wallis G, et al. Single-Cell Transcriptomic Analyses Define Distinct Peripheral B Cell Subsets and Discrete Development Pathways. Front. Immunol. 2021;12:602539. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Integrating Centrifuge Independent and Time Efficient Automated Washing in Flow Cytometry Crossmatching
Now Watchinghttps://www.youtube.com/watch?v=xaq_8XIfIDA Description Dr. Prabhakar Putheti, Assistant Director for Immunogenetics and Transplantation Laboratory (IGT), the Rogosin Institute and Assistant Professor, Weill Cornell Medical College, presents, “Integrating Centrifuge-Independent and Time Efficient Automated Washing in Flow Cytometry Crossmatching”. Dr. Putheti will discuss how the Laminar Wash system improved his workflow for flow cytometry crossmatching.