Tag: immune cells

POSTER 2026 – Automated Antibody Cocktailing and C-FREE™ Workflow for Immuno-engineering Applications

SCIENTIFIC POSTER Automated Antibody Cocktailing and C-FREE™ Workflow for Immuno-engineering Applications This poster demonstrates how the Curiox Pluto workstation automates antibody cocktailing and C-FREE™ cytometry sample preparation for immuno-engineering applications. Data show reproducible NK-cell and memory T-cell immunophenotyping — comparable to manual methods across donors and markers — with reduced hands-on time and an integrated […]

Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics

Wang, M., Otto, C., Zapata, C. F., Dehlinger, A., Gallaccio, G., Diekmann, L., Niederschweiberer, M., Schindler, P., Körtvélyessy, P., Kunkel, D., Paul, F., Ruprecht, K., & Böttcher, C. (2025). Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics. iScience, 112383. https://doi.org/10.1016/j.isci.2025.112383 Ocrelizumab, an anti-CD20 antibody, depletes CD20+ B […]

Immunopeptidomic MHC-I Profiling and Immunogenicity Testing Identifies Tcj2 as a New Chagas Disease mRNA Vaccine Candidate

Versteeg, L., Adhikari, R., Robinson, G., Lee, J., Wei, J., Islam, N., Keegan, B., Russell, W. K., Poveda, C., Villar, M. J., Jones, K., Bottazzi, M. E., Hotez, P., Tijhaar, E., & Pollet, J. (2024). PLoS Pathogens, 20(12), e1012764. https://doi.org/10.1371/journal.ppat.1012764 Trypanosoma cruzi is a protozoan parasite that causes Chagas disease. Globally 6 to 7 million […]

Profiling Circulating T cells and Tumor Landscape for Predicting Responses to PD-1 blockade in Patients with Non-Small Cell Lung Cancer

Dutta, N. (2024, September 5). https://gupea.ub.gu.se/handle/2077/81804 Immune checkpoint blockade (ICB) has significantly improved outcomes in non-small cell lung cancer (NSCLC), yet only a subset of patients achieves durable responses. This underscores the need for effective methods to assess ICB efficacy. This thesis investigates the response to PD-1 blockade in NSCLC patients across stages I to […]

Could Debris Be Masking Your True Results

Now Watchinghttps://www.youtube.com/watch?v=TlQaihGArto Sample preparation is the stage that can make or break an assay’s performance. Preserving the natural state of samples without having to sacrifice population size can be the difference between innovation and stagnation. Now more than ever, we need dependable, reproducible results that don’t require a lab magician. With Laminar Wash, we can […]

Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction

READ NATURE PORTFOLIO PREPRINT Researchers at the University of Chicago used their Laminar Wash HT2000 system to safely prepare peripheral immune cells from COVID-19 patients with moderate and severe disease for flow cytometry in a biosafety cabinet. This preprint manuscript in a Nature family journal reveals how increased IL-6 and CCL2 in patients with severe […]

Centrifuge-less Immuno-staining of Cells for Superior Viability, Recovery & Data

Now Watchinghttps://www.youtube.com/watch?v=kAUfEX1oQKY This webinar is presented by Sue Reynolds, Ph.D. Sue has extensive flow cytometry experience working in industry as a flow core manager, application scientist, field marketing and market development manager. Watch this webinar to learn about: Impacts of centrifugation on your cell samples and data Introduction to the working principles and products of […]