Breathe Easy with Better Models

Now Watching Research for Activating Macrophages and Dendritic Cells with Nanomedicine in Lung Carcinoma https://youtu.be/wljKOIcYsUM Macrophages can mediate phagocytosis of cancer cells and cytotoxic tumor killing, and engage in effective bidirectional interactions with components of the innate and adaptive immune system. Given the continuous recruitment of myelomonocytic cells into tumor tissues, macrophages are candidates for […]
Curiox Biosystems to Advance Next-Generation Cancer Cell Therapies Through Collaboration with Leading Cancer Researcher

BOSTON, Sep. 13, 2023 /PRNewswire/ — Curiox Biosystems, a global leader in providing innovative and automated sample preparation solutions for accurate and reproducible cell analysis, is pleased to announce its collaboration with Dr. Marco Ruella, an Assistant Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn), to support efforts in the […]
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer
Lim JS, Ibaseta A, Fischer MM, et al. Nature. 2017;545(7654):360-364. READ NATURE Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
PP4 inhibition sensitizes ovarian cancer to NK cell-mediated cytotoxicity via STAT1 activation and inflammatory signaling
READ PUBMED Cancerous tumors grow and prosper in an inflammatory environment at the intersection of many signaling pathways in the immune system. Since tumors exist in such a complex environment, researchers have been interested in how targeting components and molecules in these signaling pathways could enable targeted therapy for cancer patients. The main challenge in […]
White Paper—Improved Sample Preparation for Immuno-oncology Studies

Download the White Paper: Improved sample preparation for immuno-oncology studies
How to wash away barriers to therapeutic cancer vaccine development

Developing neoantigen-based cancer vaccines necessitates comprehensive cellular characterization for iterative therapeutic improvement, which Laminar Wash™ systems may facilitate at multiple steps. Vaccines are probably the second-most effective advancement in the annals of human medicine, after sanitation. Most of us recognize the value of vaccines in infectious disease. Yet, swept under the rug amongst the COVID-19 global pandemic is another form of immune-boosting injection combating a terrible […]
Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease
READ JOVE Jones K, Versteeg L, Damania A, et al. Infection and Immunity. 2018;86(4). Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Functional profiling of nucleotide Excision repair in breast cancer
READ JOVE Rajkumar-Calkins AS, Szalat R, Dreze M, et al. DNA Repair. 2019;82:102697. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Nucleotide excision repair is a potential therapeutic target in multiple myeloma
READ JOVE Szalat R, Samur MK, Fulciniti M, et al. Nucleotide excision repair is a potential therapeutic target in multiple myeloma. Leukemia. 2017;32:111. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.
Follicular fluid metabolome and cytokinome profiles in poor ovarian responders and the impact of dehydroepiandrosterone supplementation
READ JOVE Viardot-Foucault V, Zhou J, Bi D, et al. Follicular fluid metabolome and cytokinome profiles in poor ovarian responders and the impact of dehydroepiandrosterone supplementation. bioRxiv. 2020:2020.2011.2003.366047. Subscribe to our newsletter Get updates about upcoming webinar technical application information and product announcements when you subscribe to the Curiox newsletter.