Shared Principles, Consistent Results: Pluto Wash vs. Laminar Wash
By Melvin Lye, Senior Director of Scientific Affairs Introduction: Questioning a Long-Held Belief For decades, suspension cell workflows followed a rigid belief: centrifugation and pelleting were the only way to wash cells. This dogma shaped countless assays but also introduced variability, operator fatigue, and cell loss. Curiox challenged this in 2018 with Laminar Wash™ (LW), proving that […]
POSTER—2025 – Reducing Operator-Dependent Variability in Immunophenotyping Through Automated Antibody Panel Preparation
Manual antibody cocktailing in high-dimensional flow cytometry often introduces user-to-user variability and consumes valuable hands-on time. This study evaluated an automated workflow using the Curiox C-FREE™ Pluto Workstation for antibody cocktailing, benchmarking it against manual methods across 10- and 24-color panels. Results showed that: Reproducibility improved: Replicate cocktail variation consistently stayed below 5%. Data quality […]
Pluto Code Secures First Global Biopharma Adoption, Redefining the Future of Centrifuge-Less Automation
Curiox Biosystems today announced the first commercial sale of Pluto Code — a licensing solution for centrifuge-less washing on liquid handlers — to a top-15 global biopharmaceutical company. The order marks a key milestone in the shift away from bulky, centrifuge-dependent automation toward software-driven simplicity. Industry Adoption The adoption by a leading global biopharma demonstrates […]
Pluto Automation: An Introduction to Centrifuge-Less Sample Prep
Automation shouldn’t take 12 months or cost $250k. Pluto reimagines what’s possible in the lab. This short overview introduces how Pluto delivers centrifuge-less cell washing and sample prep automation—making advanced automation accessible for every lab. https://youtu.be/2PxERlWVKkI Why Centrifuge-Less Matters for Cell Washing Traditional centrifuges can stress cells, slow down workflows, and introduce variability. Pluto replaces […]
Advancing Antibody Cocktail Solutions: Empowering CROs with Pluto Automation
By Melvin Lye, Senior Director of Scientific Affairs The preclinical CRO market is projected to reach USD 8.4 billion by 2030, driven by the rise in high-throughput studies and the demand for reproducible biomarker data in drug development. Yet, many Contract Research Organizations (CROs) still rely on manual pipetting for antibody cocktailing, creating bottlenecks that threaten […]
Automating Flow Cytometry Sample Prep: An ROI Calculation
Automating Flow Cytometry Sample Prep: An ROI Calculation Manual flow cytometry sample preparation is labor-intensive and costly, with multiple touchpoints for antibody cocktail prep, cell lysis, and staining. Each manual step adds labor cost, training time, and risk of error. Here we highlight the ROI of automated sample preparation, showing how Pluto Workstation reduces hands-on […]
Unlock Reproducibility in Flow Cytometry — Watch Now
Now Watching https://youtu.be/RTJU6rHmqTE Flow cytometry workflows often suffer from inconsistent results. Variability in cell preparation, preservation, staining, and analysis can compromise your data — and your research. In this short, must-watch video, Dr. Holden Maecker of Stanford HIMC reveals why these issues persist and how automation and standardization can deliver reproducible, high-quality flow cytometry data. […]
Automating Antibody Cocktail Preparation for Flow Cytometry – White Paper
WHITEPAPER Automating Antibody Cocktail Preparation for Flow Cytometry This whitepaper shows how C-FREE™ Pluto Workstations (LT/MT/HT) automate antibody master mix generation with easy workflow setup and walk-away execution—delivering stain indices equivalent or better than manual prep, lower CVs on key markers, and major reductions in hands-on time—all at costs comparable to conventional pipette workstations. See […]
Automated Antibody Cocktailing with C-FREE™ Pluto Workstation
Now Watching https://youtu.be/Z0N0gNL5a5c Streamline your flow cytometry sample preparation with the Curiox C-FREE™ Pluto Workstation—the first fully automated platform for antibody cocktailing and washing without centrifugation. This short animated video shows how Pluto eliminates manual pipetting, spinning, and washing, replacing it with automated, walkaway prep that’s consistent, gentle on cells, and incredibly efficient. Perfect for […]
Beyond Centrifuges: How Smart Automation Transforms Lab Efficiency
By Vincent Andreala, Field Application Scientist | Edited by Melvin Lye, Senior Director of Scientific Affairs June 17, 2025 Introduction: Why Automation, Why Now? If you’ve ever found yourself wrestling with inconsistent data, backlogged experiments, or a constant hunt for trained personnel to manage delicate workflows—you’re not alone. The traditional approach to cell sample preparation has […]