Pluto Code Secures First Global Biopharma Adoption, Redefining the Future of Centrifuge-Less Automation
Curiox Biosystems today announced the first commercial sale of Pluto Code — a licensing solution for centrifuge-less washing on liquid handlers — to a top-15 global biopharmaceutical company. The order marks a key milestone in the shift away from bulky, centrifuge-dependent automation toward software-driven simplicity. Industry Adoption The adoption by a leading global biopharma demonstrates […]
POSTER—2025 – Evaluating the Curiox C-FREE Pluto System for Whole Blood Immunophenotyping Sample Processing
Flow cytometry remains a critical tool for immunological research and diagnostics, yet traditional manual workflows can be labor-intensive and inconsistent. The Curiox C-FREE Pluto System (Pluto) introduces a fully-automated workflow solution, including antibody cocktailing, seamlessly integrating with conventional protocols without requiring adaptation. Pluto incorporates gentle washing of samples as opposed to harsh centrifugal forces with […]
POSTER—2025 CYTO – Evaluating the Curiox C-FREE Pluto System for Whole Blood Immunophenotyping Sample Processing
Flow cytometry remains a critical tool for immunological research and diagnostics, yet traditional manual workflows can be labor-intensive and inconsistent. The Curiox C-FREE Pluto System (Pluto) introduces a fully-automated workflow solution, including antibody mastermix prep, seamlessly integrating with conventional protocols without requiring adaptation. Pluto incorporates gentle washing of samples as opposed to harsh centrifugal forces […]
Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics
Wang, M., Otto, C., Zapata, C. F., Dehlinger, A., Gallaccio, G., Diekmann, L., Niederschweiberer, M., Schindler, P., Körtvélyessy, P., Kunkel, D., Paul, F., Ruprecht, K., & Böttcher, C. (2025). Comprehensive analysis of B cell repopulation in ocrelizumab-treated patients with multiple sclerosis by mass cytometry and proteomics. iScience, 112383. https://doi.org/10.1016/j.isci.2025.112383 Ocrelizumab, an anti-CD20 antibody, depletes CD20+ B […]
IMU Biosciences Adopts Curiox’s Pluto for Large-Scale UK Immune Profiling Initiative
Leading AI-Powered Immune Profiling Company IMU to Adopt Pluto Workstation for Large-Scale Immune Phenotyping Project Based on UK Patient Big Data SEOUL, South Korea, May 15, 2025 (GLOBE NEWSWIRE) — Curiox Biosystems Co., Ltd. (“Curiox”) announced on March 28 that it has officially received a Sales Order for its Pluto Workstation (“Pluto”) from IMU Biosciences […]
POSTER—2025 SLAS – Evaluating the Curiox C-FREE Pluto System for Whole Blood Immunophenotyping Sample Processing
Flow cytometry remains a critical tool for immunological research and diagnostics, yet traditional manual workflows can be labor-intensive and inconsistent. The Curiox C-FREE Pluto System (Pluto) introduces a fully-automated workflow solution, including antibody cocktailing, seamlessly integrating with conventional protocols without requiring adaptation. Pluto incorporates gentle washing of samples as opposed to harsh centrifugal forces with […]
Immunopeptidomic MHC-I Profiling and Immunogenicity Testing Identifies Tcj2 as a New Chagas Disease mRNA Vaccine Candidate
Versteeg, L., Adhikari, R., Robinson, G., Lee, J., Wei, J., Islam, N., Keegan, B., Russell, W. K., Poveda, C., Villar, M. J., Jones, K., Bottazzi, M. E., Hotez, P., Tijhaar, E., & Pollet, J. (2024). PLoS Pathogens, 20(12), e1012764. https://doi.org/10.1371/journal.ppat.1012764 Trypanosoma cruzi is a protozoan parasite that causes Chagas disease. Globally 6 to 7 million […]
A novel mass cytometry protocol optimized for immunophenotyping of low-frequency antigen- specific T cells
Balz, K., Grange, M., Pegel, U., Karamya, Z. A., Mello, M., Zhou, X., Berger, T., Bloch, K., Dunham, D., Chinthrajah, S., Nadeau, K., Luche, H., & Skevaki, C. (2024b). Frontiers in Cellular and Infection Microbiology, 13. https://doi.org/10.3389/fcimb.2023.1336489 Understanding antigen-specific T-cell responses, for example, following virus infections or allergen exposure, is of high relevance for the […]
Nanomedicine-based co-delivery of a calcium channel inhibitor and a small molecule targeting CD47 for lung cancer immunotherapy
Guo, Y., Bao, Q., Hu, P., & Shi, J. (2023). Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-42972-2 Pro-tumoral macrophages in lung tumors present a significant challenge in immunotherapy. Here, we introduce a pH-responsive nanomedicine approach for activating anti-tumoral macrophages and dendritic cells. Using a layered double hydroxide nanosheet carrier, we co-deliver a T-type calcium channel inhibitor (TTA-Q6) and […]
Critical Quality Metrics in Cell Sample Prep for Cell & Gene Therapy Bioanalytics
Now Watchinghttps://youtu.be/vEgp_FSQHF8 In this panel discussion, Virginia Litwin, Ph.D. (CRL), Christoph Eberle, MICR, FRSPH (CRL), Mahwish Natalia, MA, Ph.D. (Takeda Oncology), and Melvin Lye, MBA (Curiox Biosystems) discuss the role of partnerships between early- and late-stream analytical assay developers. While tackling unique challenges in validating flow cytometric methods for Chimeric Antigen Receptor (CAR) T cells, […]